Influence of Hibiscus sabdariffa (Gongura) on the levels of circulatory lipid peroxidation products and liver marker enzymes in experimental hyperammonemia

Essa, Musthafa Mohamed; Subramanian, Perumal; Ganapathy, Suthakar; Manivasagam, Thamilarasan; Dakshayani, Kadiyala Babu; Sivaperumal, R.; Subash, Selvaraju; Govindarajah, Vinothini

doi:10.32725/jab.2006.004

Cited by 14 publications

(10 citation statements)

References 31 publications

(28 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…H. sabdariffa (gongura), of the family Malvaceae, an annual dicotyledonous herbaceous shrub plant popularly known as 'Gongura' in Telugu, 'Pitwa' in Hindi or 'Pulicha keerai' in Tamil is native to Asia and Africa and is commonly used to make jellies, jams, and beverages. Different parts of this plant have been recommended as a remedy for various ailments such as hypertension, pyrexia and liver disorders (Essa et al, 2006). In traditional medicine, this plant has features useful in several applications, including an antidote for poisonous chemicals (acids, alkali, pesticides) and mushrooms (Essa et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

“…Different parts of this plant have been recommended as a remedy for various ailments such as hypertension, pyrexia and liver disorders (Essa et al, 2006). In traditional medicine, this plant has features useful in several applications, including an antidote for poisonous chemicals (acids, alkali, pesticides) and mushrooms (Essa et al, 2006). M. oleifera belonging to the single genus family Moringaceae is a small, fast-growing ornamental tree originally found in India.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Phytochemicals, antioxidant and antimicrobial activity of Hibiscus sabdariffa, Centella asiatica, Moringa oleifera and Murraya koenigii leaves

Zhang¹,

Hettiarachchy²,

Horax³

et al. 2011

J. Med. Plants Res.

View full text Add to dashboard Cite

Many exotic vegetables remain uninvestigated as potential sources of bioactive nutrients. The objective was to determine and compare nutrients, selected phytochemicals and antioxidant and antimicrobial activities in three types of leafy vegetables and a spice, including Hibiscus sabdariffa, Centella asiatica, Moringa oleifera, and Murraya koenigii. Proximate analysis, vitamin C, beta-carotene, phenolics and flavanoids contents including antioxidant capacity and antimicrobial activity were determined. Soluble dietary fiber, vitamin C and lutein contents were highest in the leaf of H. sabdariffa including high contents of flavanoids and phenolic acids. M. oleifera leaf had the highest contents of carotenoids, (-) epicatechin and o-coumaric acid while M. koenigii's leaf had the highest content of benzoic acid. The anti-radical power values were 1.03, 0.63, 0.41, and 1.19 mg DPPH/mg extract for the ethanolic extracts from C. asiatica, M. koenigii, H. sabdariffa, and M. oleifera leaves, respectively. Total phenolic contents of the ethanolic extracts significantly affected their anti-radical power with a strong positive correlation between the total phenolic contents and their anti-radical power values. Antimicrobial activity of the three leaf extracts against Listeria monocytogenes, Salmonella typhimurium, and E. coli O157:H7 resulted in H. sabdariffa L. to exhibit the most antibacterial activity among all extracts evaluated in this study showing pathogen reduction to non-detectable limits. These leaves can be used as potential sources of vitamins, minerals, phenolics with antioxidant activity and as antimicrobial agents with potential medicinal value.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Phytochemicals, antioxidant and antimicrobial activity of Hibiscus sabdariffa, Centella asiatica, Moringa oleifera and Murraya koenigii leaves

Zhang¹,

Hettiarachchy²,

Horax³

et al. 2011

J. Med. Plants Res.

View full text Add to dashboard Cite

show abstract

“…In China, it is used to treat hypertension, pyrexia, and liver damage (Tsai and Ou, 1996;El Hakim, 2010) and lately its sepal extract has been used as an effective treatment against leukemia, due to its high content in polyphenols, particularly protocatechic acid (Odigie et al, 2003). Hibiscus sabdariffa is usually taken as a drink made from the calyx, especially in the western part of Africa and has been recommended as a remedy for various ailments such as hypertension, pyrexia and liver disorders (Essa et. al., 2006;Obouayeba et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

“…al., 2006;Obouayeba et al, 2014). It has also been said to be a mild diuretic and purgative, among many other effects (Essa et al, 2006). The in vivo pharmacological activities as antipyretic, antioxidant and anticholesterol products were screened in rats and rabbits (Ali et al, 2005;Ochani and D'Mello, 2009 ).…”

Section: Introductionmentioning

confidence: 99%

A comparative study on morphology, mineral and vitamin compositions of two variants of Hibiscus sabdariffa (L.)

Ilodibia¹,

Achebe²,

Arubalueze³

et al. 2019

Arch. Agri. Environ. Sci.

View full text Add to dashboard Cite

Morphological, mineral and vitamin compositions of leaves and seeds of two varieties of Hibiscus sabdariffa L. were evaluated using standard techniques and compared. Analysis of variance was employed in data analyses. Morphological study showed no significant difference in their habit, structure and phyllotaxy but varied mostly in sizes and colour. The red variety had a greater leaf area (94.25±0.310cm 2) and petiole length (6.50±0.620cm) than the green variety, whose leaf area and petiole length are 53.95±0.400cm 2 and 3.60±0.332cm respectively. The minerals and vitamins were found to be present in all the parts of the two varieties investigated but in varying levels. Higher composition of the minerals and vitamins were found in the leaves than the seed. However, the nutrients were higher in the red variety. The results of the study revealed that these parts of the two varieties investigated are nutritious and can contribute significantly to the human health requirements thus could be extracted for the manufacture of food and drugs supplements. Overall data could be used as a viable tool in Roselle breeding for improvement in Roselle production and also to enhance proper taxonomic characterization and identification of the plant species which have immense economic potentials as ornamental plants.

show abstract

“…[1] Among liver diseases, alcoholinduced liver injury is one of the world's major health problems and excessive alcohol consumption caused several fetal diseases, which are evidenced by considerable experimental and clinical studies. [2,3] High alcohol consumption results in critical problems in the body including alcohol liver diseases (ALD). [4] Many pathways are thought to be involved in ALD, including oxidative stress and mitochondrial damage.…”

Section: Introductionmentioning

confidence: 99%

Effect of Vimliv on lipid profile and histopathology in ethanol-induced hepatotoxicity in albino Wistar rats

Samundeeswari¹,

Rajadurai²,

Ganapathy³

et al. 2013

Int J Nutr Pharmacol Neurol Dis

View full text Add to dashboard Cite

Background: Liver disease is considered to be a serious health problem, as the liver is an important organ for the detoxifi cation and deposition of endogenous and exogenous substances. Objective: The present study is carried out to investigate the effect of Vimliv in ethanol-induced hepatotoxicity. Materials and Methods: Ethanol (3 g/kg) was dissolved in water and injected intragastrically, for a period of 35 days. Vimliv was dissolved in carboxy methyl cellulose and administered to rats at doses of 25 and 50 mg/kg for a period of 35 days as coadministration. Results: Administration of Vimliv resulted in signifi cant reduction of blood glucose, serum urea, creatinine, lipid profi le and increase in albumin. Administration of Vimliv also shows better pathological effects on liver and kidney. Conclusion: Therefore, this study suggests that Vimliv has the hepatoprotective effect and consequently may alleviate liver and renal damage associated with ethanol-induced hepatotoxicity in rats.

show abstract

Influence of Hibiscus sabdariffa (Gongura) on the levels of circulatory lipid peroxidation products and liver marker enzymes in experimental hyperammonemia

Cited by 14 publications

References 31 publications

Phytochemicals, antioxidant and antimicrobial activity of Hibiscus sabdariffa, Centella asiatica, Moringa oleifera and Murraya koenigii leaves

Phytochemicals, antioxidant and antimicrobial activity of Hibiscus sabdariffa, Centella asiatica, Moringa oleifera and Murraya koenigii leaves

A comparative study on morphology, mineral and vitamin compositions of two variants of Hibiscus sabdariffa (L.)

Effect of Vimliv on lipid profile and histopathology in ethanol-induced hepatotoxicity in albino Wistar rats

Contact Info

Product

Resources

About