Influence of IGF-I on buffalo (Bubalus bubalis) spermatozoa motility, membrane integrity, lipid peroxidation and fructose uptake in vitro

Selvaraju, Sellappan; Reddy, I. J.; Nandi, S.; Rao, S. B. N.; Ravindra, J.P.

doi:10.1016/j.anireprosci.2008.08.011

Cited by 57 publications

(65 citation statements)

References 48 publications

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“…Studies have indicated that IGF-I has the ability to improve sperm motility by accelerating the consumption of energy substrates by sperm cells. However, the formation of free radicals can be stimulated (Selvaraju et al, 2009;Minelli et al, 2011). In the present work, the use of IGF-I and vitamin E had little effect on sperm motility.…”

Section: Discussionmentioning

confidence: 67%

“…It has also been shown that, immediately after the addition of this hormone in semen, sperm quality is improved in equine (Macpherson et al, 2002), buffalo (Selvaraju et al, 2009) and boar (Silva et al, 2011). Thus, a method to improve the quality of cooled boar semen could be the addition of a metabolic activator such as IGF-I, along with an antioxidant such as vitamin E.…”

Section: Introductionmentioning

confidence: 99%

“…Several chemical substances have been linked to metabolic control of the sperm cell, including the growth factor insulin-like type I (IGF-I) in bovine (Henricks et al, 1998) and swine (Silva et al, 2011). According to previous studies in buffalo, this substance acts as a metabolic activator of sperm that is involved in cell movement (motility and intensity of movement) by increasing carbohydrate metabolism, and consequently, the fertilising capacity of the sperm (Selvaraju et al, 2009). However, cellular energy metabolism is related to the generation of a higher amount of free radicals (O'Flaherty et al, 1997), which could affect semen quality and fertilising ability of spermatozoa.…”

Section: Introductionmentioning

confidence: 99%

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Effect of the addition of IGF-I and vitamin E to stored boar semen

Mendez

Zangerônimo

Rocha

et al. 2013

Animal

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The objective of this study was to evaluate the addition of IGF-I to pig insemination doses stored at 158C, in conjunction with the addition of different amounts of vitamin E (a-tocopherol). Semen samples (n 5 12) from four boars were treated by the addition of different concentrations of vitamin E, ranging up to 400 mg/ml. Immediately after processing and after the doses had been stored at 158C for 24 or 72 h, samples were warmed at 378C and 30 ng/ml of IGF-I was added. The assessments were made after 10 and 120 min of IGF-I addition. There was a minor effect of the vitamin E added before cooling and IGF-I added after storage on sperm quality. The addition of 400 mg/ml of vitamin E to diluted semen reduced ( P , 0.01) the malondialdehyde (MDA) production in boar semen stored at 158C for 72 h, regardless of the addition of IGF-I as additive during a 120 min incubation period at 378C. In these conditions, IGF-I also reduced ( P , 0.05) the MDA production in semen samples without addition of vitamin E. IGF-I in the presence of vitamin E reduced ( P 5 0.03) the glucose intake in freshly diluted boar semen samples before cooling. It was concluded that the addition of 400 mg/ml of vitamin E reduces the MDA production in boar semen stored at 158C for 72 h, regardless of the presence of IGF-I additive. The addition of IGF-I in doses stored for 72 h with vitamin E ensures higher sperm motility after 120 min of incubation at 378C.

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Section: Discussionmentioning

confidence: 67%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effect of the addition of IGF-I and vitamin E to stored boar semen

Mendez

Zangerônimo

Rocha

et al. 2013

Animal

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“…In other studies, total IGF-I was measured. For instance, in buffaloes, Selvaraju et al (2009) (Henricks et al, 1998) in bovine seminal plasma, and in stallion from 10.2 to 10.4 ng/mL (Macpherson et al, 2002). These values show that the levels in boars and stallions are similar to those in humans (Lackey et al, 2002), but much lower than those found in cattle and buffaloes.…”

Section: Discussionmentioning

confidence: 74%

“…It was suggested that IGF-I might maintain motility through energy uptake or due to its antioxidant effect in these species, with these effects being linked to spermatozoal metabolism, capacitation and acroso-mal reaction (Selvaraju et al, 2009), which would be related to the attachment and penetration of the oocyte. These authors observed that IGF-I increased the fructose uptake and decreased the lipid peroxidation level of buffalo spermatozoa.…”

Section: Discussionmentioning

confidence: 99%

Identificação do fator de crescimento semelhante à insulina i no plasma seminal de varrões e sua influência na qualidade espermática

et al. 2012

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A presente pesquisa foi realizada para investigar as relações entre os parâmetros dos espermatozóides e as concentrações de IGF-I no plasma seminal de varrões. Amostras de sêmen (duplicatas) foram coletadas de machos maduros (n=27). Em cada ejaculação, as características macroscópicas e microscópicas foram determinadas. Após a centrifugação para separar espermatozóides do plasma seminal, as concentrações de IGF-I em amostras de plasma seminal foram determinadas por kit de imunoensaio humano específico. A concentração média de IGF-I do plasma seminal de varrões foi de 1,5±0,2 ng/mL (n=54 amostras). Não houve correlação (p>0,05) entre IGF-I com a maioria dos parâmetros avaliados. Houve apenas uma correlação baixa negativa (-0,29, p=0,0331) entre a concentração de IGF-I no plasma seminal e a taxa de degradação da motilidade. Este estudo sugere que o IGF-I no plasma seminal de varrões não está relacionado com os parâmetros seminais iniciais do sêmen in natura. No entanto, o hormônio aumentou a duração da motilidade espermática.

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Serum IGF‐I in middle age covaries with reproductive life‐history traits in british men and women

Rickard

2012

American J Hum Biol

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These results are consistent with the hypothesis that the GH/IGF-I axis partially underlies individual variance in reproductive outcomes, through either direct endocrine effects on reproductive function or behavior, indirect effects on other traits, or a combination of the above. Several limitations of this study include the late age at which blood samples were collected and the difficulty of disentangling social and biological factors contributing to the traits studied. Am. J. Hum. Biol., 2012. © 2012 Wiley Periodicals, Inc.

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Influence of IGF-I on buffalo (Bubalus bubalis) spermatozoa motility, membrane integrity, lipid peroxidation and fructose uptake in vitro

Cited by 57 publications

References 48 publications

Effect of the addition of IGF-I and vitamin E to stored boar semen

Effect of the addition of IGF-I and vitamin E to stored boar semen

Identificação do fator de crescimento semelhante à insulina i no plasma seminal de varrões e sua influência na qualidade espermática

Serum IGF‐I in middle age covaries with reproductive life‐history traits in british men and women

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