The field experiment entitled “Influence of Nitrogen levels and Microbial inoculants on Yield and Economics of French bean" was conducted during rabi season, 2022 at Crop Research Farm in the Department of Agronomy, Naini Agriculture Institute, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj Uttar Pradesh. The soil in the experimental area was sandy loam with pH (8.0), Organic Carbon (0.42%), Available N (180.58 kg/ha), Available P (15.54 kg/ha), and Available K (198.67 kg/ha). The treatment consisted of two factors, Factor-1 levels of Nitrogen (75,100,125 kg/ha) and factor-2 Microbial inoculants (Rhizobium, PSB & Rhizobium +PSB). The experiment was layout in Randomized Block Design (RBD) with 10 treatments and replicated thrice. It was noticed that application of Nitrogen levels and Microbial inoculants had a significant effect on growth, yield, and yield parameters. The results indicated that the higher seed yield (22.47 q/ha), stover yield (50.08 q/ha), harvest index (30.95%), gross return (133601.00 INR/ha), net return (91333.00 INR/ha) and benefit-cost ratio (2.16) were observed in treatment 6, which involved the seed inoculation of Rhizobium and PSB along with the soil application of Nitrogen 100 kg/ha. So, in order to get higher productivity and returns from French bean, application of 100kg N/ha along with seed inoculation with phosphate solubilizing bacteria (PSB) and Rhizobium should be followed in sub-humid condition of Prayagraj, UP.