Influence of ivermectin and clorsulon treatment on productivity of a cow-calf herd on the southern Oregon coast

Rickard, Lora G.; Zimmerman, Gary L.; Hoberg, Eric P.; Bishop, Janell K.; Pettitt, Richard J.

doi:10.1016/0304-4017(92)90007-v

Cited by 14 publications

(7 citation statements)

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“…In addition, such effects resulted in fewer changes in spermatozoal functions and resulted in DNA integrity in the frozen-bull spermatozoal subsequently better spermatozoa motility in the bulls administrated with ivermectin. These results are in agreement with those of Rickard et al (1992), who showed that ivermectin administration increased conception rates. Moreover, Janett et al (2001) ivermectin treatment had a favorable effect on stallion fertility.…”

Section: Discussionsupporting

confidence: 93%

Freezability, Dna Integrity and Fertilizing Capacity of Spermatozoa of Friesian Bulls Treated With Anti - Helminthic Drugs

El-Dein¹,

Zeidan²,

El-Desouki

et al. 2011

Journal of Animal and Poultry Production

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Effect of three different anti-helminthic drugs (ivermectin, levamisole and albendazole) on quality and fertility of spermatozoa of frozen-thawed semen of Frisian bulls .Animals were divided into four groups, control untreated group, and bulls treated with 200 µg/kg of ivermectin (IVM), 7.5 mg/kg of levamisole (LEV), and 10 mg/kg of albendazole (ABZ), respectively. The drugs used at two doses with 8-week interval between first and second dose. Semen was collected for 8 th weeks after each dose, extended, and frozen for two months, then post-thawing motility, freezability, intact acrosome and DNA integrity were determined. After the second dose, bulls treated with IVM and LEV significantly (P<0.05) increased post-thawing motility, freezability and intact acrosome. Bulls treated with IVM did not negatively influenced DNA integrity, while LEV treatment affected negatively on DNA integrity by increasing tail moment percentage. Either first or second doses of ABZ did not negatively affect post-thawing motility, freezability, intact acrosome and DNA integrity. Fertility rates of the cows artificially inseminated with the frozen-thawed semen were significantly (P<0.05) higher when they were inseminated with semen of bulls treated with IVM or LEV and untreated bulls (control) than those treated with ABZ. In conclusion, treatment of Friesian bulls with Ivermectin as anti-helminthic drug at a level of 200 µg/kg live body weight improved post-thawing motility and freezability of spermatozoa, percentage of spermatozoa with intact acrosome, and maintained DNA integrity and subsequent fertilizing efficiency of bull spermatozoa as compared to control bulls or bulls treated with Levamisole (7.5 mg/kg) or Albendazole (10 mg/kg) either after the first or second dose.

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Section: Discussionsupporting

confidence: 93%

Freezability, Dna Integrity and Fertilizing Capacity of Spermatozoa of Friesian Bulls Treated With Anti - Helminthic Drugs

El-Dein¹,

Zeidan²,

El-Desouki

et al. 2011

Journal of Animal and Poultry Production

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“…The effect of strategic anthelmintic treatment of beef cattle and cow-calf pairs on body weight gain is well established and has recently been underlined by studies conducted in North America (Ciorda et al, 1987;Stuedemann et al, 1989;Rickard et al, 1992;Stromberg et al, 1997). Reinemeyer (1992) compared the effects of anthelmintic treatment of beef cattle on performance parameters and presented a cost-benefit analysis.…”

Section: Discussionmentioning

confidence: 99%

“…Reinemeyer (1992) compared the effects of anthelmintic treatment of beef cattle on performance parameters and presented a cost-benefit analysis. Some investigators also analysed the reproductive performance under the conditions of anthelmintic treatment in North America and found that treated animals conceived approximately 2 weeks earlier (Rickard et al, 1992) and that the average pregnancy rate per year was higher, compared with untreated controls (Stromberg et al, 1997). However, the need for a strategic anthelmintic control of strongyle infections in cow-calf systems in Central Europe has been a matter of discussion for some time Scharf et al, 1995).…”

Section: Discussionmentioning

confidence: 99%

Cow–Calf Herds in Eastern Germany: Status Quo of Some Parasite Species and a Comparison of Chemoprophylaxis and Pasture Management in the Control of Gastrointestinal Nematodes

Wacker¹,

Roffeis

Conraths

1999

Journal of Veterinary Medicine, Series B

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Infections with gastrointestinal parasites (Eimeria spp., Cryptosporidium spp., Buxtonella sulcata, Fasciola hepatica, Moniezia spp. and trichostrongyles) and lungworms were monitored in five cow-calf herds in the north German lowlands. Estimated prevalences of infections with Eimeria spp. (predominantly Eimeria bovis) ranged between approximately 2 and 48%. The highest prevalences were found during late summer and autumn. On one farm Cryptosporidium spp. were detected in July and August (prevalence: 8.5 +/- 2.7% and 6.7 < 2.0%). The latter finding coincided with diarrhoea in many calves. Buxtonella sulcata was found during the entire study period in highly variable estimated prevalences ranging between zero and 73%, but without any obvious association with clinical disease. Fasciola hepatica was detected on four out of five farms at estimated prevalences of approximately 1-20%. Lungworm infections played a minor role in at least three of five study herds. The estimated prevalence of trichostrongyle infections rose from August until November whereas the intensity of infection did not change significantly. No difference in the intensity of infection could be detected between one farm on which infections with gastrointestinal nematodes were controlled only by moving the animals to an uninfected pasture in July, and three other herds on which strategic anthelmintic control was in place.

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“…In vitro and in vivo experiments, it has been found that Diaveridine induces damage to chromosome structures in mammalian cells. [23,24] However, such widespread drug use in animal influences humans directly and indirectly, and both positively and negatively; [20,25,26] factors such as dose, dosage form, the route of administration, frequency and indications of medications affect the pharmacokinetics and pharmacodynamics of drugs. Similarly to mebendazole, it can be applied to both humans and animals.…”

Section: Introductionmentioning

confidence: 99%

“…[20][21][22] The advanced veterinary medical care promotes improved health in animals and allows for enhanced efficiency in animal husbandry. [23,24] However, such widespread drug use in animal influences humans directly and indirectly, and both positively and negatively; [20,25,26] factors such as dose, dosage form, the route of administration, frequency and indications of medications affect the pharmacokinetics and pharmacodynamics of drugs. [20,27] Also, human errors in farming and manufacturing as well as failures in following prescription instructions can leave drug residues in food supplies.…”

Section: Introductionmentioning

confidence: 99%

Development of high performance liquid chromatography‐ultraviolet detection method for screening mebendazole, clorsulon, diaveridine, and tolfenamic acid in animal‐based food samples

Kang

Huh

et al. 2013

Drug Testing and Analysis

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This study focused on the detection and validation of the residues of the four veterinary drugs, mebendazole, clorsulon, diaveridine, and tolfenamic acid, using high performance liquid chromatography (HPLC) and an ultraviolet (UV) detector. Utilizing C18 column as a stationary phase and applying appropriate mobile phases to each analysis according to the properties of the analytes, target compounds in food samples were successfully detected and separated within 15-50 min. Additionally, in order to optimize detection, liquid-liquid extraction (LLE) and purification steps were established to minimize the endogenous peaks and their interferences. The method was validated through testing of linearity, accuracy, precision, the limit of detection (LOD) and the limit of quantification (LOQ). The LOQ levels of the four drugs were lower than the maximum residual limit, and the coefficient of determination (R(2) ) was over 0.99. The recovery results ranged from 82.3-105.2%, 79.3-83.3%, 79.4-86.0%, and 81.7-88.5% with relative standard deviations lower than 20% for mebendazole, clorsulon, diaveridine, and tolfenamic acid, respectively, corresponding to the CODEX guideline. This proposed method reduces costs and enables easier application in rural or remote areas where testing facilities or instruments often are unavailable.

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Influence of ivermectin and clorsulon treatment on productivity of a cow-calf herd on the southern Oregon coast

Cited by 14 publications

References 1 publication

Freezability, Dna Integrity and Fertilizing Capacity of Spermatozoa of Friesian Bulls Treated With Anti - Helminthic Drugs

Freezability, Dna Integrity and Fertilizing Capacity of Spermatozoa of Friesian Bulls Treated With Anti - Helminthic Drugs

Cow–Calf Herds in Eastern Germany: Status Quo of Some Parasite Species and a Comparison of Chemoprophylaxis and Pasture Management in the Control of Gastrointestinal Nematodes

Development of high performance liquid chromatography‐ultraviolet detection method for screening mebendazole, clorsulon, diaveridine, and tolfenamic acid in animal‐based food samples

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