Influence of magnesium sulphate infusion before total thyroidectomy on transient hypocalcemia — a randomised study

Bešič, Nikola; Zagar, Spela; Pilko, Gasper; Perić, Barbara; Hočevar, Marko

doi:10.2478/v10019-008-0010-8

Cited by 9 publications

(3 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The finding of a significant impact of hypomagnesemia on postthyroidectomy hypocalcemia should prompt further study to investigate if aggressive treatment of hypomagnesemia in patients with hypocalcemia may minimize this complication. There is one previously published study that investigated the impact of intravenous magnesium sulfate at the beginning of surgery on postoperative hypocalcemia, and found no difference in incidence of hypocalcemia between the groups . However, this was a small study, with magnesium administered at the time of surgery in a nonselective fashion, and so it is unlikely that this study could exclude a benefit for magnesium supplementation in the subset of patients developing hypocalcemia and hypomagnesemia.…”

Section: Discussionmentioning

confidence: 91%

Impact of postoperative magnesium levels on early hypocalcemia and permanent hypoparathyroidism after thyroidectomy

2015

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 91%

Impact of postoperative magnesium levels on early hypocalcemia and permanent hypoparathyroidism after thyroidectomy

2015

View full text Add to dashboard Cite

show abstract

“…However, Xiaofei7 showed that postoperative hypomagnesemia was not a risk factor of hypocalcemia, and thus, that there is no need to monitor serum Mg levels regularly during perioperative period. Preoperative preventive Mg supplements could even raise the risk of postoperative hypocalcemia 12. Therefore, more research is essential to demonstrate the relationship between Mg and postoperative hypocalcemia, and more importantly, to reach a consensus on how to prevent postoperative hypocalcemia.…”

mentioning

confidence: 99%

<p>Magnesemia: an independent risk factor of hypocalcemia after thyroidectomy</p>

Wang¹,

Meng²,

Ouyang³

et al. 2019

CMAR

View full text Add to dashboard Cite

Background This study was designed to investigate the impact of serum magnesium (Mg) levels on hypocalcemia after thyroidectomy. Patients and methods In total, 242 patients with differentiated thyroid cancer were retrospectively analyzed. Results Multivariate regression analysis showed hypomagnesemia was an independent risk factor for hypocalcemia ( P <0.001). While Mg in low levels (0.66 mmol/L ≤ Po-Mg ≤0.74 mmol/L) increased the risk of hypocalcemia, postoperative serum Ca (Po-Ca) levels were significantly lower in patients with hypomagnesemia than in patients with normomagnesemia ( P =0.01), and the former patients suffered significant decreases in serum Ca ( P =0.02). Compared to patients with a mild decline of serum Mg after surgery (ΔMg <0.17), serum Ca decline significantly increased ( P <0.001) in patients with a severe decline of serum Mg (ΔMg ≥0.17), while the change in amounts of parathyroid hormone (PTH) after surgery was similar between the two groups ( P >0.05). In patients with normal Po-Ca levels, hypomagnesemia increased the risk of symptoms related to hypocalcemia by 4.478 times (OR =5.478, 95% CI 1.724–17.403). Conclusion Hypomagnesemia, or even a low serum Mg level within the normal range, can increase the risk of hypocalcemia. After excluding the potential effects of PTH on serum magnesium and calcium, serum Mg reduction is one of the most important factors that influences postoperative serum Ca reduction. What’s more, hypomagnesemia is closely linked with symptoms.

show abstract

“…Therefore, a surgical resection is regarded as the best treatment for a metastatic tumour, especially, if isolated, the solitary thyroid metastasis was found. There is also still a doubt about the extent operation in thyroid surgery because of the complications after total thyroidectomy 20. If the metastasis is known preoperatively, lobectomy and isthmectomy are enough but when the diagnosis is doubtful or multifoci of metastasis are found, total tyhroidectomy is the choice of the surgical treatment.…”

Section: Discussionmentioning

confidence: 99%

Metastatic tumours to the thyroid gland: report of 3 cases and brief review of the literature

Vardar¹,

Erkan²,

Bayol³

et al. 2011

Radiology and Oncology

View full text Add to dashboard Cite

BackgroundMetastases to the thyroid are encountered rarely in clinical practice, but the number of cases seems to have increased in recent years. The reason of this increase may be a more frequent use of fine-needle aspiration biopsy (FNAB) and the use of more sophisticated, complicated imaging techniques in patients with thyroid masses. Also, in addition to these reasons, the use of more organo-specific immunohistochemical antibodies in the examination of surgical specimens may affect the differential diagnosis of malignant tumours.Case reportsThree metastatic tumours to thyroid were found in the retrospective review of malignant thyroid tumours diagnosed between January 1993 and December 2007. The primary tumours were clear cell carcinoma of the kidney, squamous cell carcinoma of the lung and breast carcinoma-ductal type.ConclusionsA detailed clinical history, careful histological examination and essential immunohistochemistry helped in attaining the correct diagnosis.

show abstract

Influence of magnesium sulphate infusion before total thyroidectomy on transient hypocalcemia — a randomised study

Cited by 9 publications

References 23 publications

Impact of postoperative magnesium levels on early hypocalcemia and permanent hypoparathyroidism after thyroidectomy

Impact of postoperative magnesium levels on early hypocalcemia and permanent hypoparathyroidism after thyroidectomy

<p>Magnesemia: an independent risk factor of hypocalcemia after thyroidectomy</p>

Metastatic tumours to the thyroid gland: report of 3 cases and brief review of the literature

Contact Info

Product

Resources

About