Influence of membrane-repairing medications on the expression of proteins of plasmolemma of enterocytes during the formation of colostral immunity

Abstract

The indices of the content of proteins with molecular mass of 10-15 and 15-24 kDa in the plasmolemma of enterocytes of the small intestine of newborn calves in the dynamics from the birth till the age of 1 day were investigated. The study was performed on three groups of calves (the control group and two experimental ones) of Ukrainian black-and-white dairy breed by drawing the samples of enterocytes of jejunum and determining protein content of membrane lysate fraction by electrophoresis. The application of native liposomes based on soybean lecithin and "Membranostabil" medication for newborn calves with colostrum increases the expression of plasmolemic proteins of enterocytes with a molecular mass of 10-15 kDa. The dynamics of comparative analysis between fractions of protein expression with molecular mass of 10-15 and 15-24 kDa in the plasmolemma of the enterocytes of the jejunum of control and experimental groups of calves is shown. The result of application of native liposomes with phospholipid bilayer based on soybean lecithin and "Membranostabil" medication allows to assume the positive effect of these means on the level of colostral immunoglobulins in the serum of newborn calves.