Static coarsening is an important physical phenomenon that influences microstructural evolution and mechanical properties. How to simulate this process effectively has become an important topic which needs to be dealt with. In this paper, a new cellular automaton (CA) model, which considers the effect of solute drag and anisotropic mobility of grain boundaries, was developed to simulate static grain coarsening of titanium alloys in the beta-phase field. To describe the effect of the drag caused by different solute atoms on coarsening, their diffusion velocities in beta titanium were estimated relative to that of titanium atoms (Ti). A formula was proposed to quantitatively describe the relationship of the diffusion velocity of Ti to that of solute atoms; factors influencing the diffusion velocity such as solute atom radius, mass, and lattice type were considered. The anisotropic mobility of grain boundaries was represented by the parameter c 0 , which was set to 1 for a fully anisotropic effect. These equations were then implemented into the CA scheme to model the static coarsening of titanium alloys Ti-6Al-4V, Ti17 (Ti-5Al-4Mo-4Cr-2Sn-2Zr, wt%), TG6 (Ti-5.8Al-4.0Sn-4.0Zr-0.7Nb-1.5Ta-0.4Si-0.06C, wt%) and TA15 (Ti-6Al-2Zr-1Mo-1V, wt%) in the beta field. The predicted results, including coarsening kinetics and microstructural evolution, were in good agreement with experimental results. Finally, the effects of time, temperature, and chemical composition on grain coarsening and the limitations of the model were discussed. The mechanical properties of titanium alloys such as the creep resistance, fracture toughness and crack propagation resistance are determined by their grain sizes in the beta phase field [1,2]. However, the grains are prone to static coarsening when held in the beta phase field because of the structural characteristics of beta-titanium and relatively high stacking fault energy at high temperatures [3]; this results in a marked decrease in the mechanical properties of final products. Therefore, it is necessary to understand and to control static coarsening of titanium alloys in a single phase field to obtain the expected mechanical properties. Previously, many experimental investigations have focused on the static coarsening behaviors of titanium alloys in the beta phase field. Ivasishin et al. [4,5] investigated the effect of texture evolution on the values of the static coarsening exponent n and activation energy for Ti-6Al-4V alloy in the beta field. They found values of n ranging from 0.22 to 0.31 at different temperatures, but there were marked deviations attributed to different materials and experiments when the results were compared with those of others. Recently, Semiatin et al. [6][7][8] investigated the static grain coarsening of Ti-6Al-4V alloy via a series of heat treatments at typical temperatures. They found that the coarsening process of primary alpha particles was controlled by the volume diffusion of solute elements at lower temperatures and the growth exponent was equal to 0.33.