According to the literature review, a nutritional support for patients after hepatopancreoduodenal surgery requires a differentiated approach. The paper presents data on the experience in providing nutritional support to this kind of patients. It is necessary to stress that nutritional risk screening should be performed prior to surgical intervention. The nutrition is recommended to be adjusted to protein and energy needs of the patient, taking into account concomitant diseases. Products for sip feeding are the method of choice. Enteral nutrition is preferable in the postoperative period. The nutritional support for patients undergoing pancreatoduodenal resection is increasingly recognized, and a randomized clinical trial is to be carried out to evaluate the effectiveness of enteral and parenteral nutrition. As a component of the enhanced recovery program, nutritional support can optimize outcomes in patients who have undergone hepatopancreatoduodenal resection. The nutritional status of a patient should be mandatorily assessed before surgery. Perioperative correction of nutritional status implies continuity and a multidisciplinary approach.