One of the often employed flow structures in vertical pumping stations is the siphon outlet pipe. It has a complicated geometric structure and internal flow field, which directly affects how effectively, safely, and steadily pumping stations operate. The entire flow conduit of the vertical axial flow pump device was adopted as the study object in order to elucidate the mechanism of the internal biased flow of the siphon outlet pipe caused by the axial flow pump under different flow conditions, and the three-dimensional unsteady flow field of the vertical axial flow pump device was numerically solved using the numerical simulation technique. Physical model tests were used to confirm the results of the numerical simulation. The findings demonstrate that there is a horizontal bias in the flow of the inlet surface and outlet surface of the elbow pipe of the siphon outlet pipe, and that when the flow rate rises, the degree of the horizontal bias in the flow gradually diminishes, and the ratio of biased flow gradually decreases. The flow in hump segment presents up-and-down flow, and when the flow rate increases, the ratios of biased flow first rises before falling. The major causes of the production of biased flow in the outlet pipe are residual velocity circulation at the guide vane's outlet, wall constraint at the elbow pipe, and flow inertia; Under various flow conditions, the morphologies of the vortex structures in the outlet pipe vary; the characteristics of the energy conversion of each part of the pump device are disclosed, with the inlet pipe having the lowest proportion of energy conversion. Under the optimal flow condition, the elbow-inlet pipe's proportion of energy conversion is only around 1.04%, and the proportions of the guide vane, 60° elbow pipe, and siphon outlet pipe's energy conversion are significant and fluctuate with time. The proportion of energy conversion in the elbow-inlet pipe and siphon outlet pipe steadily increases as flow rate rises, but the proportion in the guide vane and 60° elbow pipe drops initially before increasing.