Influence of selenium yeast on the growth, selenium uptake and mineral composition of Coriolus versicolor mushroom

Abstract

The ability of Coriolus versicolor medicinal mushroom to grow and accumulate selenium during submerged cultivation in a selenium‐fortified medium is examined in this paper. For selenium supplementation, commercial selenium yeast was used. Control, nonenriched sample and reference cultures cultivated in the medium enriched with commercial yeast Saccharomyces cerevisiae were also prepared. The mushroom demonstrated a high ability to accumulate selenium from the added source (around 970 and 1,300 µg/g of dry mycelium weight for samples enriched with selenium in a concentration of 10 and 20 mg Se/L, respectively). The addition of selenium significantly (p ≤ .05) increased the biomass yield, whereas the addition of nonenriched yeast had no significant (p ≤ .05) impact. Furthermore, regression analysis showed statistically significant (p ≤ .05) and positive correlations between the content of Se and Fe (r = .92), Se and Cu (r = .92), Se and Mn (r = .98), and Se and Sr (r = .96), suggesting that selenium incorporation was followed by incorporation of these elements, and led to mineral enrichment of the obtained mycelium. Methanol extracts prepared from mycelium biomass demonstrated a better inhibitory effect on Gram‐positive bacterial strains with minimal inhibitory concentrations between <0.3125 and 40 mg/ml. The obtained results showed that selenium yeast could be used for obtaining a potential novel food supplement: mushroom biomass with high selenium content and enhanced mineral composition.

Metabolic Response of the Yeast Candida utilis During Enrichment in Selenium

“…The bioaccumulation of Se by various microorganisms has been widely studied by many authors. As reported by Miletić et al [45], the medicinal fungus Coriolus versicolor grown in medium supplemented with 10 and 20 mg Se/L could accumulate 970 and 1300 µg/g of Se, respectively. Ullah et al [46] showed that the probiotic bacteria Bacillus subtilis BSN313 grown in Se-enriched medium at the dose of 12 µg/mL could bind 2.123 µg Se/g.…”

Bioactivity of Biomass and Crude Exopolysaccharides Obtained by Controlled Submerged Cultivation of Medicinal Mushroom Trametes versicolor

“…The easily digestible proteins of mushrooms are determined as the main carrier of the mushroom’s nutritional value because they could provide all essential amino acid requirements [ 68 ]. Apart from the nutritional value, there are reports about bioactive proteins and peptides demonstrating pharmacological potential [ 68 , 85 , 86 , 87 ]. The protein content of the wild fruiting body and mycelium biomass obtained through submerged cultivation usually varies.…”

Engineered Selenium/Human Serum Albumin Nanoparticles for Efficient Targeted Treatment of Parkinson’s Disease via Oral Gavage

“…The studies outlined above generally show that HSA/Se NPs have good biosafety, although some reports indicate that Se has therapeutic effects in PD. 32 Furthermore, the range between therapeutic and toxic doses is narrow and cannot effectively reach the midbrain lesion area. Therefore, this study compared the therapeutic effects of HSA/Se NPs, nano-Se, and Selenious yeast in subacute PD model mice.…”