Influence of synovia constituents on tribological behaviors of articular cartilage

Murakami, Teruo; Yarimitsu, Seido; Nakashima, Kouichi; Sawae, Yoshinori; Sakai, Nobuo

doi:10.1007/s40544-013-0010-6

Cited by 61 publications

(54 citation statements)

References 42 publications

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“…In particular, γ-globulin led to reduction of friction value. However, in the following study [28], where the separate impact of the constituents was evaluated, the effect of γ-globulin was shown to be the opposite. In the next paper [29], the effect of a PHs in combination with proteins was investigated.…”

Section: Introductionmentioning

confidence: 86%

“…The lubricants and the cartilage specimens were thawed at room temperature for 30 min and were stored in a fluid bath to avoid dehydration. Each experiment consisted of five steps-three friction (loading) steps and two unloading steps in order to enable cartilage rehydration [18,28]. Focusing on daily activities such as walking, the articular cartilage is repeatedly loaded and unloaded within very short time intervals.…”

Section: Methodsmentioning

confidence: 99%

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The Effect of Synovial Fluid Composition, Speed and Load on Frictional Behaviour of Articular Cartilage

et al. 2020

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Articular cartilage ensures smooth motion of natural synovial joints operating at very low friction. However, the number of patients suffering from joint diseases, usually associated with cartilage degradation, continuously increases. Therefore, an understanding of cartilage tribological behaviour is of great interest in order to minimize its degradation, preserving the reliable function of the joints. The aim of the present study is to provide a comprehensive comparison of frictional behaviour of articular cartilage, focusing on the effect of synovial fluid composition (i), speed (ii), and load (iii). The experiments were realized using a pin-on-plate tribometer with reciprocating motion. The articular cartilage pin was loaded against smooth glass plate while the tests consisted of loading and unloading phases in order to enable cartilage rehydration. Various model fluids containing albumin, γ-globulin, hyaluronic acid, and phospholipids were prepared in two different concentrations simulating physiologic and osteoarthritic synovial fluid. Two different speeds, 5 mm/s and 10 mm/s were applied, and the tests were carried out under 5 N and 10 N. It was found that protein-based solutions exhibit almost no difference in friction coefficient, independently of the concentration of the constituents. However, the behaviour is considerably changed when adding hyaluronic acid and phospholipids. Especially when interacting with γ-globulin, friction coefficient decreased substantially. In general, an important role of the interaction of fluid constituents was observed. On the other hand, a limited effect of speed was detected for most of the model fluids. Finally, it was shown that elevated load leads to lower friction, which corresponds well with previous observations. Further study should concentrate on specific explored phenomena focusing on the detailed statistical evaluation.

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Section: Introductionmentioning

confidence: 86%

Section: Methodsmentioning

confidence: 99%

The Effect of Synovial Fluid Composition, Speed and Load on Frictional Behaviour of Articular Cartilage

et al. 2020

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“…Solution of both proteins reported even lower friction than γ-globulin. In the following paper (Murakami, 2013) authors mixed protein solutions with hyaluronic acid and phospholipids with different impacts on friction. However, the lowest values of friction coefficient were obtained for solution consisted of all 4 substances.…”

Section: Engineering Mechanics 2018mentioning

confidence: 99%

Optoelectronic measurement of interfacial surface

2018

Engineering Mechanics

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“…Meanwhile, the regime of boundary lubrication was suggested by Hardy in the 1920s [6], immediately followed by numerous experimental and theoretical researches. Boundary lubrication regime was well established based on the concept that the lubricant layer adsorbed physically or chemically, on the rubbing surfaces, which is capable of supporting the high load [7][8][9][10][11].…”

Section: Historic Reviewmentioning

confidence: 99%

Advances in thin film lubrication (TFL): From discovery to the aroused further researches

2015

Sci. China Technol. Sci.

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Thin film lubrication (TFL) is known as a mode of fluid-film lubrication regime bridging the gap between elastohydrodynamic lubrication (EHL) and boundary lubrication (BL). Since the first recorded literature published in 1995, TFL has become one of the landmarks in the development of lubrication theory over the last twenty years. This article presents an overview of the advances in the research of TFL regime. We first begin with a brief introduction of the discovery of the phenomenon, followed by the discussion of the relevant essential aspects, such as the performing approach, theory and physical model. The state-of-the-art studies on both the theoretical and experimental fields are also presented, also latter with emphasis on the review of researches in several promising applications. thin film lubrication, film thickness, ordered structure, interface Citation:Ma L R, Luo J B. Advances in thin film lubrication (TFL): From discovery to the aroused further researches.

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Influence of synovia constituents on tribological behaviors of articular cartilage

Cited by 61 publications

References 42 publications

The Effect of Synovial Fluid Composition, Speed and Load on Frictional Behaviour of Articular Cartilage

The Effect of Synovial Fluid Composition, Speed and Load on Frictional Behaviour of Articular Cartilage

Optoelectronic measurement of interfacial surface

Advances in thin film lubrication (TFL): From discovery to the aroused further researches

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