2018
DOI: 10.3390/jcm8010032
|View full text |Cite
|
Sign up to set email alerts
|

Influence of Traditional Cardiovascular Risk Factors on Carotid and Femoral Atherosclerotic Plaque Volume as Measured by Three-Dimensional Ultrasound

Abstract: Background: Atherosclerosis is a systemic multifocal disease with a preference for the branching points of the arteries. In this study, we quantitatively measured carotid and femoral plaque volume in subjects with cardiovascular risk factors (CVRF) and/or established atherosclerotic disease using a 3D ultrasound technique. Methods: In this prospective, single-centre study, we included 404 patients (median age 64; 56.9% men) with at least one CVRF or established cardiovascular disease. Plaque volume was measure… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

2
19
0
1

Year Published

2020
2020
2024
2024

Publication Types

Select...
7

Relationship

2
5

Authors

Journals

citations
Cited by 15 publications
(22 citation statements)
references
References 28 publications
2
19
0
1
Order By: Relevance
“…Moreover, stratified analyses and interaction tests showed that the stronger association between male sex and vulnerable plaque did not change by age, family history of stroke, histories of chronic disease (ischemic stroke or TIA, hypertension, dyslipidemia, diabetes mellitus), smoking status, drinking, physical activity, and BMI, suggesting that male is associated with a higher risk of vulnerable plaque independent of classical vascular risk factors. It has been demonstrated that age, hypertension, diabetes, high low-density lipoprotein cholesterol levels, and current smoking are traditional cardiovascular risk factors related to the prevalence of carotid plaques (Sturlaugsdottir et al, 2016;Bian et al, 2018;Noflatscher et al, 2019;Santos-Neto et al, 2021). However, there is scarce information regarding the gender differences in the prevalence of carotid plaques in participants at high risk of stroke, especially vulnerable plaque.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Moreover, stratified analyses and interaction tests showed that the stronger association between male sex and vulnerable plaque did not change by age, family history of stroke, histories of chronic disease (ischemic stroke or TIA, hypertension, dyslipidemia, diabetes mellitus), smoking status, drinking, physical activity, and BMI, suggesting that male is associated with a higher risk of vulnerable plaque independent of classical vascular risk factors. It has been demonstrated that age, hypertension, diabetes, high low-density lipoprotein cholesterol levels, and current smoking are traditional cardiovascular risk factors related to the prevalence of carotid plaques (Sturlaugsdottir et al, 2016;Bian et al, 2018;Noflatscher et al, 2019;Santos-Neto et al, 2021). However, there is scarce information regarding the gender differences in the prevalence of carotid plaques in participants at high risk of stroke, especially vulnerable plaque.…”
Section: Discussionmentioning
confidence: 99%
“…Previous epidemiological researches have reported the associations between several classical vascular risk factors (such as age, hypertension, diabetes, dyslipidemia, and current smoking) and carotid plaques (Sturlaugsdottir et al, 2016;Bian et al, 2018;Noflatscher et al, 2019;Santos-Neto et al, 2021). It is noted that the incidence of stroke is higher in male individuals compared with the female age < 75 years (Lloyd-Jones et al, 2010), and gender differences in plaque characteristics might help explain this phenomenon.…”
Section: Introductionmentioning
confidence: 99%
“…Therefore, we hope that we can provide data on the association of NGAL with plaque progression in the near future. To reliably document plaque progression, we decided to perform sonographic 3D plaque volumetry, which is a practicable and new approach for the exact determination of plaque volume in peripheral and carotid arteries [ 18 , 29 ]. Recent studies showed a strong association between peripheral plaque measurement via sonographic 3D ultrasound and calcium score assessment by computed tomography [ 30 ].…”
Section: Discussionmentioning
confidence: 99%
“…Patients were recruited from the prospective observational single-center cohort study “Correlation of Atherosclerotic Plaque Volume and Intima Media Thickness With Soluble P-selectin trial” (Clinical trials.gov identifier: NCT01895725; approved by the ethics committee of the Medical University of Innsbruck on 31/May/2013, approval number UN5048). The baseline results of this trial have been reported [ 18 ].…”
Section: Methodsmentioning
confidence: 99%
“…This disease could also increase the risk of death among middle-aged and older patients [7]. Atherosclerotic arterial occlusion could be attributed to several risk factors, including hypertension [8], diabetes [8][9][10], dyslipidemia [8,11], smoking [8,9,12], homocysteine [13], chronic reactive protein (CRP) [14], sex [7], and race [15,16]. Predominant symptoms and signs may be variable.…”
Section: Introductionmentioning
confidence: 99%