The mesoscale eddies have a remarkable influence on the sound field underwater, and many previous studies investigate the effects of eddies on transmission loss (TL), convergence zone, time delay, etc. However, the effects of eddies on spatial coherence are less studied and remain unclear. In this paper, the effects of eddies on spatial coherence at the subsurface in deep water is investigated. The eddy environments are simulated with Gaussian eddy equations, the complex pressure field is obtained using a range dependent parabolic equation (PE) model, and the associated mechanism is analyzed based on ray theories and models. The results show that the cold/warm mesoscale eddies affect the spatial coherence in high intensity zone, by changing the locations and width of the convergence zone. In the shadow zone, the horizontal correlation radius (HCR) and the vertical correlation radius (VCR) increases with range and decreases with depth, and they are increased by warm eddies and decreased by cold eddies, mainly caused by variation of multipath structure.