Influences of ambient temperature, charge density on wettability properties of monolayer MoS&lt;inf&gt;2&lt;/inf&gt; films

Ye, Haiming; Zhao, Meiwen; Li, Minglin; Wang, Weidong

doi:10.1109/nems.2017.8017093

Cited by 3 publications

(3 citation statements)

References 21 publications

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“…The higher hydrophobicity of DHAM/PCL-MoS 2 is due to the hydrophobic nature of MoS 2 nanosheets. 61,62 The plasma treatment of electrospun samples decreased their water contact angle below 60° that is acceptable for cell attachment.…”

Section: Discussionmentioning

confidence: 99%

Decellularized human amniotic membrane reinforced by MoS₂-Polycaprolactone nanofibers, a novel conductive scaffold for cardiac tissue engineering

et al. 2022

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In order to regenerate myocardial tissues with functional characteristics, we need to copy some properties of the myocardium, such as its extracellular matrix and electrical conductivity. In this study, we synthesized nanosheets of Molybdenum disulfide (MoS2), and integrated them into polycaprolactone (PCL) and electrospun on the surface of decellularized human amniotic membrane (DHAM) with the purpose of improving the scaffolds mechanical properties and electrical conductivity. For in vitro studies, we seeded the mouse embryonic cardiac cells, mouse Embryonic Cardiac Cells (mECCs), on the scaffolds and then studied the MoS2 nanocomposites by scanning electron microscopy and Raman spectroscopy. In addition, we characterized the DHAM/PCL and DHAM/PCL-MoS2 by SEM, transmission electron microscopy, water contact angle measurement, electrical conductivity, and tensile test. Besides, we confirmed the scaffolds are biocompatible by 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide, MTT assay. Furthermore, by means of SEM images, it was shown that mECCs attached to the DHAM/PCL-MoS2 scaffold have more cell aggregations and elongated morphology. Furthermore, through the Real-Time PCR and immunostaining studies, we found out cardiac genes were maturated and upregulated, and they also included GATA-4, c-TnT, NKX 2.5, and alpha-myosin heavy chain in cells cultured on DHAM/PCL-MoS2 scaffold in comparison to DHAM/PCL and DHAM. Therefore, in terms of cardiac tissue engineering, DHAM nanofibrous scaffolds reinforced by PCL-MoS2 can be suggested as a proper candidate.

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Section: Discussionmentioning

confidence: 99%

Decellularized human amniotic membrane reinforced by MoS₂-Polycaprolactone nanofibers, a novel conductive scaffold for cardiac tissue engineering

et al. 2022

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“…The incorporation of MoS 2 nanoparticles into nylon nanofibers decreased the wettability of scaffolds and thereby the water contact angle was increased from 57°to 75°owing to the hydrophobic nature of MoS 2 nanosheets. [41,42] The oxygen plasma treatment increased the hydrophilicity of the nylon/ MoS 2 nanofibers to 68°. A positive slope was obtained from MTT assay of mECCs proliferation on nylon and nylon/MoS 2 scaffolds, evidencing no cytotoxicity effect of the scaffolds.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Nanofibrous Composites Reinforced by MoS₂ Nanosheets as a Conductive Scaffold for Cardiac Tissue Engineering

et al. 2019

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Mimicking the structure of extracellular matrix and electrical conductivity of myocardium are required to regenerate the functional cardiac tissue. In this study, Molybdenum disulfide, MoS2, nanosheets were synthesized and incorporated into nylon6 electrospun nanofibers in order to enhance the mechanical properties and electrical conductivity of the scaffolds. Then, the mouse embryonic cardiac cells, mECCs, were seeded on the scaffolds for in vitro studies. The MoS2 nanosheets were studied by scanning electron microscopy (SEM) and Raman spectroscopy. Nylon/MoS2 nanofibers were characterized by SEM, transmission electron microscopy (TEM), water contact angle measurement, electrical conductivity, and tensile test. Furthermore, cytocompatibility of scaffolds was confirmed by 3‐(4, 5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyl tetrazolium bromide, MTT, assay. SEM images showed more elongated morphology for mECCs attached to the nylon/MoS2 scaffold. Also, the Real‐Time PCR and immunostaining studies indicated the maturation and upregulation of cardiac functional genes including GATA‐4, c‐TnT, Nkx 2.5 and α‐MHC in the nylon/MoS2 scaffold in comparison to the bare nylon. Therefore, MoS2 reinforced nylon nanofibrous scaffolds can be considered as a suitable candidate in cardiac tissue engineering.

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Incorporation of two‐dimensional nanomaterials into silk fibroin nanofibers for cardiac tissue engineering

Nazari

Heirani‐Tabasi

Hajiabbas

et al. 2019

Polymers for Advanced Techs

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Mimicking the extracellular matrix to have a similar nanofibrous structure regarding electrical conductivity and mechanical properties would be highly beneficial for cardiac tissue engineering. The molybdenum disulfide, MoS 2 , and reduced graphene oxide, rGO, nanosheets are two-dimensional nanomaterials which can be considered as great candidates for enhancing the electrical and mechanical properties of biological scaffolds for cardiac tissue engineering applications. In this study, MoS 2 and rGO nanosheets were synthesized and incorporated into silk fibroin nanofibers, SF, via electrospinning method. Then, the human iPSCs transfected with TBX-18 gene, TBX18-hiPSCs, were seeded on these scaffolds for in vitro studies. The MoS 2 and rGO nanosheets were studied by Raman spectroscopy. After incorporation of the nanosheets into SF nanofibers, the associated characterizations were carried out including scanning electron microscopy, transmission electron microscopy, water contact angle, and mechanical test. Furthermore, SF, SF/MoS 2 , and SF/rGO scaffolds were used for in vitro studies. Herein, the scaffolds exhibited acceptable biocompatibility and considerable attachment to TBX18-hiPSCs confirmed by 3-(4, 5dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide, MTT, assay, and scanning electron microscopy. Also, the real-time PCR and immunostaining studies confirmed the maturity and upregulation of cardiac functional genes, including GATA-4, c-TnT, and α-MHC in the SF/MoS 2 and SF/rGO scaffolds compared with the bare SF one.Therefore, the reinforcement of these SF-based scaffolds with MoS 2 and rGO endues them as a suitable candidate for cardiac tissue engineering.

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Influences of ambient temperature, charge density on wettability properties of monolayer MoS<inf>2</inf> films

Cited by 3 publications

References 21 publications

Decellularized human amniotic membrane reinforced by MoS₂-Polycaprolactone nanofibers, a novel conductive scaffold for cardiac tissue engineering

Decellularized human amniotic membrane reinforced by MoS₂-Polycaprolactone nanofibers, a novel conductive scaffold for cardiac tissue engineering

Nanofibrous Composites Reinforced by MoS₂ Nanosheets as a Conductive Scaffold for Cardiac Tissue Engineering

Incorporation of two‐dimensional nanomaterials into silk fibroin nanofibers for cardiac tissue engineering

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Influences of ambient temperature, charge density on wettability properties of monolayer MoS<inf>2</inf> films

Cited by 3 publications

References 21 publications

Decellularized human amniotic membrane reinforced by MoS2-Polycaprolactone nanofibers, a novel conductive scaffold for cardiac tissue engineering

Decellularized human amniotic membrane reinforced by MoS2-Polycaprolactone nanofibers, a novel conductive scaffold for cardiac tissue engineering

Nanofibrous Composites Reinforced by MoS2 Nanosheets as a Conductive Scaffold for Cardiac Tissue Engineering

Incorporation of two‐dimensional nanomaterials into silk fibroin nanofibers for cardiac tissue engineering

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Decellularized human amniotic membrane reinforced by MoS₂-Polycaprolactone nanofibers, a novel conductive scaffold for cardiac tissue engineering

Decellularized human amniotic membrane reinforced by MoS₂-Polycaprolactone nanofibers, a novel conductive scaffold for cardiac tissue engineering

Nanofibrous Composites Reinforced by MoS₂ Nanosheets as a Conductive Scaffold for Cardiac Tissue Engineering