Influences of Tumor Volume and FWHM of the Water Peak and T₂* Value of Water on the Detection Rate of the Choline Peaks in Proton MR Spectroscopy of Breast Cancer at 3.0 T-MRI

Abstract

In proton magnetic resonance (MR) spectroscopy ( 1 H-MRS) of the breast cancer, choline peak could be detected. The purpose of this study was to evaluate the influences of the tumor volume, full width at half maximum (FWHM) of the water peak (FWHM), and T2* value of water (T2* value) on the detection rate of the choline peaks at 3.0 T-MRI. We measured FWHM and T2* value in 109 cases, and we evaluated the effect of tumor volume on the detection rate of the choline peaks and the effect of FWHM and T2* value on the detection of choline peaks. In 1 H-MRS of breast cancer at 3.0 T-MRI, the detection rate of the choline peaks improved as the tumor volume was larger. As a shimming environment when acquiring 1 H-MRS of breast cancer, FWHM is preferably 57.4 Hz or less and T2* value should be 11 ms or more, and T2* value has a great influence on the detection rate of the choline peaks.