Influencia del estado nutricional sobre la estancia media hospitalaria en el paciente con diabetes mellitus tipo 2

Valles, Cristina Serrano; Gómez, Juan José López; Calvo, Susana García; Sahagún, Rebeca Jiménez; Torres, Beatriz; Hoyos, Emilia Gómez; Buigues, Ana Ortolá; Román, Daniel Antonio de Luis

doi:10.1016/j.endinu.2020.05.004

Cited by 7 publications

(2 citation statements)

References 19 publications

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“…Previous studies showed that hospitalized T2DM patients had poorer nutritional status than nondiabetic patients, which may affect UA levels. 15 Recent studies found that an increase in serum UA levels was closely related to the occurrence of metabolic syndromes other than gout, such as dyslipidaemia, abnormal glucose tolerance, hypertension, central obesity and other metabolic disorders. 16 UA also induces insulin resistance via endothelial cell mitochondrial oxidative stress.…”

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confidence: 99%

Association Between Uric Acid and Insulin-Like Growth Factor-1 in Type 2 Diabetes Mellitus

Liu¹,

Wang²,

Zhao³

et al. 2021

IJGM

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Objective: This research examined the relationship between uric acid (UA) and insulin-like growth factor-1 (IGF-1) in patients with type 2 diabetes mellitus (T2DM). Methods: This study was a cross-sectional study that included 1230 Chinese patients with T2DM. We collected general information and laboratory indicators and calculated the standard deviation score of IGF-1 (IGF-1 SDS). Results:The univariate analysis results demonstrated a significant positive relationship between UA levels and IGF-1 SDS (P<0.001). A nonlinear relationship was discovered between UA and IGF-1 SDS after adjusting for confounding factors. Multivariate piecewise linear regression showed that the levels of IGF-1 SDS increased when UA was <4.17 mg/dl (β 0.12,95% CI −0.04, 0.28; P=0.121) and decreased when UA was >4.17 mg/dl (β −0.38,95% CI −0.64, −0.12; P=0.004). Conclusion:This study showed a nonlinear relationship between UA and IGF-1 in Chinese adults with T2DM. When the UA levels reached the inflection point, IGF-1 levels negatively correlated with the increase in UA. Further studies are needed to explore this relationship and mechanisms in the future.

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confidence: 99%

Association Between Uric Acid and Insulin-Like Growth Factor-1 in Type 2 Diabetes Mellitus

Liu¹,

Wang²,

Zhao³

et al. 2021

IJGM

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“…Furthermore, diagnostic criteria for cachexia, in which inflammation due to chronic diseases as well as malignant tumors is found as an underlying pathological condition, have been developed recently [ 6 ], and the importance of cachexia has attracted attention. Sarcopenia, malnutrition, and cachexia are associated with low activities of daily living, bone fractures, hospitalization, prolonged hospitalization, increased healthcare costs, and higher mortality rates [ 7 , 8 , 9 , 10 ]. Thus, early diagnosis of and early intervention for these conditions in elderly patients with diabetes mellitus are essential tasks.…”

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confidence: 99%

Frequency and Overlap of Cachexia, Malnutrition, and Sarcopenia in Elderly Patients with Diabetes Mellitus: A Study Using AWGC, GLIM, and AWGS2019

Ida,

Imataka,

Morii

et al. 2024

Nutrients

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This study aimed to estimate the frequency and overlap of cachexia, malnutrition, and sarcopenia in elderly patients with diabetes mellitus. Patients who were aged at least 65 years, had diabetes mellitus, and were regularly visiting the Ise Red Cross Hospital on an outpatient basis were included. The patients were assessed to determine whether they had cachexia, malnutrition, and sarcopenia according to the Asian Working Group for Cachexia criteria, the Global Leadership Initiative on Malnutrition criteria, and the Asian Working Group for Sarcopenia 2019 criteria. A total of 510 patients (310 men and 200 women) were analyzed in this study. Sarcopenia, cachexia, and malnutrition were found in 84 patients (16.4%), 40 patients (7.8%) (17.8% among patients with chronic diseases), and 110 patients (21.5%), respectively. Among patients with sarcopenia, the frequencies of cachexia and malnutrition were 30% and 71.4%, respectively. Among patients with cachexia, the frequencies of sarcopenia and malnutrition were 65% and 90%, respectively, and among those with malnutrition, the frequencies of sarcopenia and cachexia were 54% and 32.7%, respectively. The overlap among cachexia, malnutrition, and sarcopenia appears to be an important factor to be considered in the treatment of elderly patients with diabetes mellitus.

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Diabetic Sarcopenia. A proposed muscle screening protocol in people with diabetes

de Luis Román,

Gómez,

García-Almeida

et al. 2024

Rev Endocr Metab Disord

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Objectives To propose the grounds for “diabetic sarcopenia” as a new comorbidity of diabetes, and to establish a muscle screening algorithm proposal to facilitate its diagnosis and staging in clinical practice. Method: A qualitative expert opinion study was carried out using the nominal technique. A literature search was performed with the terms “screening” or “diagnostic criteria” and “muscle loss” or “sarcopenia” and “diabetes” that was sent to a multidisciplinary group of 7 experts who, in a face-to-face meeting, discussed various aspects of the screening algorithm. Results: The hallmark of diabetic sarcopenia (DS) is muscle mass atrophy characteristic of people with diabetes mellitus (DM) in contrast to the histological and physiological normality of muscle mass. The target population to be screened was defined as patients with DM with a SARC-F questionnaire > 4, glycosylated haemoglobin (HbA1C) ≥ 8.0%, more than 5 years since onset of DM, taking sulfonylureas, glinides and sodium/glucose cotransporter inhibitors (SGLT2), as well as presence of chronic complications of diabetes or clinical suspicion of sarcopenia. Diagnosis was based on the presence of criteria of low muscle strength (probable sarcopenia) and low muscle mass (confirmed sarcopenia) using methods available in any clinical consultation room, such as dynamometry, the chair stand test, and Body Mass Index (BMI)-adjusted calf circumference. DS was classified into 4 stages: Stage I corresponds to sarcopenic patients with no other diabetes complication, and Stage II corresponds to patients with some type of involvement. Within Stage II are three sublevels (a, b and c). Stage IIa refers to individuals with sarcopenic diabetes and some diabetes-specific impairment, IIb to sarcopenia with functional impairment, and IIc to sarcopenia with diabetes complications and changes in function measured using standard tests Conclusion: Diabetic sarcopenia has a significant impact on function and quality of life in people with type 2 diabetes mellitus (T2DM), and it is important to give it the same attention as all other traditionally described complications of T2DM. This document aims to establish the foundation for protocolising the screening and diagnosis of diabetic sarcopenia in a manner that is simple and accessible for all levels of healthcare.

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Influencia del estado nutricional sobre la estancia media hospitalaria en el paciente con diabetes mellitus tipo 2

Cited by 7 publications

References 19 publications

Association Between Uric Acid and Insulin-Like Growth Factor-1 in Type 2 Diabetes Mellitus

Association Between Uric Acid and Insulin-Like Growth Factor-1 in Type 2 Diabetes Mellitus

Frequency and Overlap of Cachexia, Malnutrition, and Sarcopenia in Elderly Patients with Diabetes Mellitus: A Study Using AWGC, GLIM, and AWGS2019

Diabetic Sarcopenia. A proposed muscle screening protocol in people with diabetes

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