Many researchers in library and information science have claimed that studies that are holistic are critical to understanding various phenomena. On closer examination, however, the term “holistic” is used mainly as a rhetorical device in the literature, rather than as one that embraces the epistemological tenets of a holistic paradigm, and applies these to research design. This paper examines this rhetorical use, and explores what it would mean, and why it would matter, to adopt substantively holistic approaches to research. We review relevant literature in library and information science to position past uses of holistic and compare these to the conceptual intentions of holism. We also outline the concept of holism, itself, with a focus on methodological and ontological holism, which can most deeply inform research design in our discipline. Greater methodological diversity, including much wider adoption of interpretivist and critical approaches, can address the concerns underlying the use of holistic rhetoric. We illustrate this central conceptual argument with a roadmap illustrating holistic considerations throughout the research process. The paper demonstrates that it is possible to shift away from predominantly rhetorical use of holistic, toward paradigmatically holistic research, which will provide for richer analyses of critical phenomena in the discipline.