Applying the risk information seeking and processing (RISP) model, this study investigates the sociopsychological factors associated with systematic processing. Results reveal interesting moderating effects for relevant channel beliefs and perceived information gathering capacity. These findings suggest that science communication surrounding the COVID-19 pandemic needs to attend to the target audience’s beliefs about specific information channels, as well as their ability to process relevant information. However, the unsupported hypotheses also call for scholarly attention on the applicability of the RISP model to non-Western cultural contexts.