“…Topical local anesthetic application in association with chosen regional anesthetic technique decreases tourniquet pain [66]. In brachial plexus block, anesthesia of the medial cutaneous nerves by a skin infiltration of local anesthetic at the root of the arm improved arm tourniquet tolerance [67]. Other factors such as tourniquet size, inflation pressure, and duration impact on patient discomfort [68][69][70][71].…”