2015
DOI: 10.1016/j.talanta.2015.04.090
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Infrared and Raman spectroscopic methods for characterization of Taxus baccata L. – Improved taxane isolation by accelerated quality control and process surveillance

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Cited by 22 publications
(18 citation statements)
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(30 reference statements)
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“…Other methods of detection, such as vibrational spectroscopy or nuclear magnetic resonance (NMR) are less sensitive or do not provide insight into the diversity of specific taxane metabolites and are rather applied to characterize plant material than body fluids [16, 17]. However, along with the technological progress in the instrumentation and metabolomic data processing, these methods could become more practical, due to a relatively simple procedures of sample preparation and comparability of results between different instruments and analysis conditions [18].…”
Section: Discussionmentioning
confidence: 99%
“…Other methods of detection, such as vibrational spectroscopy or nuclear magnetic resonance (NMR) are less sensitive or do not provide insight into the diversity of specific taxane metabolites and are rather applied to characterize plant material than body fluids [16, 17]. However, along with the technological progress in the instrumentation and metabolomic data processing, these methods could become more practical, due to a relatively simple procedures of sample preparation and comparability of results between different instruments and analysis conditions [18].…”
Section: Discussionmentioning
confidence: 99%
“…Sh i = 2 + 1.1 ⋅ Sc 0.33 ⋅ Re 0.6 (5) Figure 6 exemplifies the experimental efforts of model parameter determination at the laboratory scale with increasing modelling depth for the rapid development over the last 10 years or so, starting with shrinking-core and pore diffusion effects taken into account [52,54], diffusion interference of different molecules by Maxwell-Stefan [55,60], shrinking and swelling mass transport kinetics of non rigid herbal raw matrices during extraction up to particle size distributions, and degradation kinetics caused by temperatures [46] up to a recent development, the spectroscopyassisted model parameter determination [44,61]. Figure 6 shows the stepwise approach of model equation assembly based on stepwise experimental model parameter determination in laboratory scale in order to develop physicochemical (rigorous) models, which are a priori predictive because of the effects of fluid-dynamics, mass transfer, phase equilibrium, and energy balances are separated from each other.…”
Section: Modelling Of the Extraction Processmentioning
confidence: 99%
“…Additionally, lignans 12 , lignins 13 , baccatin 14 , flavonoids, steroids, bicyclic & tetracyclic diterpenes 15 , biflavones and taxoids 16 and sugar derivatives have been reported in different parts of this plant. Chemical methods like LC-MS 17 , Infrared and Raman spectroscopic techniques 18 have been attempted to detect phytochemicals of T. baccata. In India, Abies webbiana (Wall ex D. Don) Lindl is commonly known as Talispatra in Hindi and Indian Silver Fir in English.…”
Section: Introductionmentioning
confidence: 99%