Inguinal Lymph Nodes in Carcinoma Penis-Observation or Surgery?

Althaf, Syed; Narayanakar, Rajkumar Parameshwar; Gangaiah, Dinesh M.; Dev, Kapil; Kurpad, Vishnu; Gurawalia, Jaiprakash

doi:10.7860/jcdr/2016/15064.7040

Cited by 2 publications

(2 citation statements)

References 25 publications

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“…En este caso clínico el paciente fue diagnosticado en sus 79 años. Tanto la enfermedad en sí como su tratamiento tienen una gran morbilidad para el paciente tanto física como psicológicamente (12). Aunque hay varios subtipos, la preponderancia de los cánceres de pene son los carcinomas de Células escamosas (13,14).…”

Section: Las Indicaciones De Alta Que Se Le Sugiere Alunclassified

Cáncer de pene. Caso clínico

Villacorta Córdova,

EnrÍquez Chugá,

Mazapanta Guanoluisa

et al. 2023

Cienc. Serv. Salud Nutr.

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Introducción: El diagnóstico de cáncer de pene es esencialmente clínico y debe confirmarse mediante el estudio histopatológico. La estadificación quirúrgica correcta es crucial y las etapas avanzadas requieren un manejo multimodal. Existen varias modalidades para el tratamiento, en la penectomía parcial es fundamental la realización de una biopsia transoperatoria para verificar mediante microscopía los márgenes de resección negativos. La quimioterapia se emplea cuando hay presencia de ganglios pélvicos positivos. Presentación del caso: paciente masculino de 79 años con antecedentes de circuncisión hace 3 años presenta dolor en región inguinal derecha y pene, de moderada intensidad. En estudios complementarios de ingreso se evidencia: PSA libre porcentual: 18.35% mientras que en los estudios de imagen se evidencia en la tomografía axial computarizada (TAC) de abdomen y pelvis, cambios degenerativos óseos a nivel de la columna dorso lumbar. Ultrasonido se evidencia adenitis inguino – crural bilateral. Se realizó biopsia del prepucio y ganglio derecho. Dentro de la impresión diagnóstica nos encontramos frente a un cáncer escamocelular pobremente diferenciado de pene estadio III (T1B-N1-M0) y P1: insuficiencia venosa GII, para lo cual se tiene como plan una penectomía parcial más vaciamiento inguinal bilateral. Conclusiones: El cáncer de pene puede presentarse como una lesión a nivel del glande. En ocasiones como úlcera perforando el prepucio con probabilidad de exteriorizarse. La detección precoz puede ayudar a reducir el avance de la enfermedad y por ende asegurar un tratamiento exitoso.

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Section: Las Indicaciones De Alta Que Se Le Sugiere Alunclassified

Cáncer de pene. Caso clínico

Villacorta Córdova,

EnrÍquez Chugá,

Mazapanta Guanoluisa

et al. 2023

Cienc. Serv. Salud Nutr.

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“…Though rare, the disease itself is a challenge years. 2 Lower incidence of the disease makes the valid estimation of prognosis of primary penile squamous cell carcinoma (PPSCC) difficult. To address this issue many investigators Kattan et al, Zini et al, and Thuret et al developed various models to predict Cancer-Specific Mortality (CSM) free rates for PPSCC.…”

Section: Introductionmentioning

confidence: 99%

The Prognostic Ability of Staging System in Men with Penile Cancer: An Analysis of SEER Database

et al. 2020

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Background: Penile cancer is now a rare condition. The low incidence of the disease makes a valid estimation of its prognosis difficult. In this study, we made an attempt and propose a nomogram to develop a prognostic rule that could predict the Cancer-Specific Mortality (CSM) free rates in patients with primary penile squalors cell carcinoma of the penis (PPSCC).Methods: This study included 1304 patients diagnosed with PPSCC between the years 2004 & 2011 and treated with penile tumor excision. Subjects were staged as per Surveillance, Epidemiology & End Results stage (SEER), American Joint Committee on Cancer (AJCC), TNM classification and tumor grade (TG). CSM free rates were determined. Univariate and multivariate Cox regression model was used to test the prediction of the CSM free rate. The predictive rule accuracy was created using the receiver operating characteristic curve. Results: The clinico-pathological profile depicts a mean age of 64.66 ± 14.38 yrs. The most common primary site involved was glans penis (n= 483, 37%) and the disease was most commonly diagnosed at AJCC stage I (n= 670, 51.4%) disease. The cumulative 5-year CSM free rates according to Fine & Gray, & Kaplan-Meier methods were 81.8% and 79.8%, respectively. The predictive accuracy as per SEER stage, AJCC stage, TNM stage alone were 68.8%, 70.3%, 72.3%, respectively. When TG was combined, the predictive accuracy increased to 72.8%, 73.1%, and 75.0%, respectively. TNM stage with TG was most accurate in predicting CSM free rate compared to other models. Conclusions: TNM stage with TG and AJCC stage with TG appear to have comparable accuracy to predict the CSM free rate in patients with PPSCC, the TNM stage with TG is the most accurate (75%) method to predict the CSM free rates. The addition of the TG variable improved the accuracy of these prognostic models.

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Inguinal Lymph Nodes in Carcinoma Penis-Observation or Surgery?

Cited by 2 publications

References 25 publications

Cáncer de pene. Caso clínico

Cáncer de pene. Caso clínico

The Prognostic Ability of Staging System in Men with Penile Cancer: An Analysis of SEER Database

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