Inhaled Aerosolized Prostacyclin as an Efficacious and Economic Alternative to Inhaled Nitric Oxide

The Use of Inhaled Prostaglandins in Patients With ARDS

“…Th is is demonstrated by the 25 publications included in the analysis, as well as the discovery of several other studies not meeting the inclusion criteria. [55][56][57][58][59][60][61][62] Th e data would also suggest that use is increasing in frequency, as approximately 75% of the patients were from studies published in the last 3 years. This is an interesting phenomenon when put into context of other fi ndings in this analysis: (1) a lack of clinical outcome data demonstrating benefi t, (2) overall low quality for the majority of data, and (3) signifi cant heterogeneity in the data that does exist.…”

Care of the Patient With Pulmonary Arterial Hypertension

“…24,26,27 Finally, NO delivery is expensive, costing several thousand dollars per day. 28,29 Even with the potential challenges of delivering this gas, NO is extensively and safely used in the neonatal ICU for the treatment of persistent pulmonary hypertension of the newborn. 24,30 In adults, current research focuses on the ability of NO to be used for long-term therapy.…”

DCCN on the Web

“…25 Five potential issues with NO exist. 28,29 Even with the potential challenges of delivering this gas, NO is extensively and safely used in the neonatal ICU for the treatment of persistent pulmonary hypertension of the newborn. Second, patients on NO may cause increased levels of methemoglobin, but this is rarely an issue for patients receiving less than 100 ppm.…”