1976
DOI: 10.1051/rnd:19760509
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Inhibition De La Protéolyse Pepsique in Vitro Par Le Blé. Rôle De l'ACIDE Phytique Des Issues

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Cited by 45 publications
(19 citation statements)
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“…This initial, rapid step is followed by a progressive protein-protein aggregation that may result in precipitation (Rajendran and Prakash, 1993). The crucial proposition is that phytate-bound protein is refractory to pepsin digestion (Camus and Laporte, 1976;Knuckles et al, 1985Knuckles et al, , 1989. Camus and Laporte (1976) attributed inhibition of pepsin digestion by phytate to the formation of insoluble protein-phytate complexes under acidic conditions.…”
Section: Underlying Mechanismsmentioning
confidence: 98%
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“…This initial, rapid step is followed by a progressive protein-protein aggregation that may result in precipitation (Rajendran and Prakash, 1993). The crucial proposition is that phytate-bound protein is refractory to pepsin digestion (Camus and Laporte, 1976;Knuckles et al, 1985Knuckles et al, , 1989. Camus and Laporte (1976) attributed inhibition of pepsin digestion by phytate to the formation of insoluble protein-phytate complexes under acidic conditions.…”
Section: Underlying Mechanismsmentioning
confidence: 98%
“…The crucial proposition is that phytate-bound protein is refractory to pepsin digestion (Camus and Laporte, 1976;Knuckles et al, 1985Knuckles et al, , 1989. Camus and Laporte (1976) attributed inhibition of pepsin digestion by phytate to the formation of insoluble protein-phytate complexes under acidic conditions. Pivotally, Vaintraub and Bulmaga (1991) reported that sodium phytate reduced in vitro pepsin hydrolysis of bovine serum albumen, casein, haemoglobin and 11S soy protein by 60 to 85% at pH 2.0 but had no influence on pepsin hydrolysis at pH 4.0 to 4.5.…”
Section: Underlying Mechanismsmentioning
confidence: 99%
“…Importantly, complexed protein is refractory to pepsin digestion (Camus and Laporte, 1976;Vaintraub and Bulmaga, 1991); presumably due to alterations in structure and solubility that render protein less susceptible to pepsin activity following aggregation with phytate. There are a number of possible consequences from the formation of protein-phytate complexes in the stomach of pigs that are refractory to pepsin digestion.…”
Section: Probable Underlying Mechanismsmentioning
confidence: 99%
“…To be safe, feed plants and poultry farms are using 0.3 to 0.4% AP formulas because of the uncertain content of nonphytate P. However, the addition of inorganic P for safety is costly. Moreover, modern poultry farming is managed intensively and a large P content in poultry manure poses an obstacle to the development of the poultry farming industry [4,5].…”
Section: Description Of Problemmentioning
confidence: 99%