Inhibition Effect of Cell Proliferation and Apoptosis by Inonotus obliquus in Human Glioblastoma U-87 MG Cells

신정아,; 박주현,; 김선희,; 송관영,

doi:10.3746/jkfn.2013.42.7.1022

Cited by 4 publications

(1 citation statement)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Более поздние исследования показали, что применение водного экстракта чаги уменьшает размер опухолей саркомы МОП и S180, карциномы лёгких Льюиса и карциномы Эрлиха, меланомы B16-F10, глиобластомы U-87 MG [33,34,[53][54][55][56], а также оказывает антиметастатическое действие in vivо: на клетки саркомы, аденокарциномы шейки матки HeLa, карциномы Эрлиха, и in vitro на клетки гепатомы, рака толстой кишки, саркомы 180 [15,30,41,53].…”

Section: Introductionunclassified

Composition and biological activity of triterpenes and steroids from Inonotus obliquus (chaga)

2016

View full text Add to dashboard Cite

Систематизированы данные по химическому составу веществ тритерпеновой и стероидной природы, выделенных из чаги, как выращенной в условиях искусственной культуры, так и произрастающей в природе. Приведены сведения по биологической активности экстрактов из чаги и этих соединений в отношении различных линий клеток рака in vitro и in vivо. Проведённый анализ позволил выявить определенные закономерности в эффективности подавления роста различных линий клеток. Установлено, что наибольшей активностью обладают тритерпеновые соединения, содержащие ОН-группу при С-22 и ненасыщенную связь в боковой цепи.Ключевые слова: чага, тритерпеновые соединения, стероидные соединения, биологическая активность, in vivo, in vitro DOI 10.18097/PBMC20166204369Рисунок. Общая структурная формула тритерпенов ланостанового ряда (а) и стероидных соединений (б).

show abstract

Section: Introductionunclassified

Composition and biological activity of triterpenes and steroids from Inonotus obliquus (chaga)

2016

View full text Add to dashboard Cite

show abstract

Studies of the composition of the cryogenic ground chaga

Razumov

Сафин

Mukhametzyanov

et al. 2020

IOP Conf. Ser.: Mater. Sci. Eng.

View full text Add to dashboard Cite

The paper studies the properties and chemical composition of birch fungus - Chaga, which contains a unique complex of biologically active substances and is used as a raw material for the production of drugs and biologically active additives. The components listed prove their antioxidant, immunomodulating, antiviral, antidiabetic, and cytotoxic properties. The paper specifies the application of chaga in such areas as medicine, agriculture and food industry. It analyses the way the method of grinding of plant raw materials might influence the quality of the resulting drugs, including the sustaining the biological activity. The results determined that the cryogenic grinding of chaga, which allows to preserve valuable substances of the fungus due to its grinding at low temperature in liquid nitrogen to be the most reasonable. The paper gives the analysis of the obtained dispersed phase by high performance liquid chromatography and atomic absorption spectroscopy. The results of the studies indicate an increase in the content of particular valuable components of the fungus in extracts of raw materials that have gone through the cryogenic grinding, compared with the extracts of raw materials obtained by the traditional grinding method. The data acquired can be of practical importance when chaga is used in medicine.

show abstract

Chemical composition and biological activity of triterpenes and steroids of chaga mushroom

Nikitina

Habibrakhmanova

Сысоева

2016

Biochem. Moscow Suppl. Ser. B

View full text Add to dashboard Cite

Inhibition Effect of Cell Proliferation and Apoptosis by Inonotus obliquus in Human Glioblastoma U-87 MG Cells

Cited by 4 publications

References 30 publications

Composition and biological activity of triterpenes and steroids from Inonotus obliquus (chaga)

Composition and biological activity of triterpenes and steroids from Inonotus obliquus (chaga)

Studies of the composition of the cryogenic ground chaga

Chemical composition and biological activity of triterpenes and steroids of chaga mushroom

Contact Info

Product

Resources

About