“…Additive or synergistic MAO inhibition (Santillo et al, 2014) might result from concurrent ingestion of ethylphenethylamines with other MAO inhibitors including drugs (Youdim et al, 2006) and β-carboline alkaloids in tobacco and botanicals (Dhawan et al, 2004;Fowler et al, 2003;Herraiz et al, 2010;McKenna et al, 1984). Furthermore, in a recent high-throughput screening campaign of 976 compounds (Sipes et al, 2013), MAO A was one of the most promiscuous targets among a total of 331 targets evaluated, which illustrates a potential for inhibition by a variety of less studied compounds.…”