Inhibition of Plant Growth by 2-Mercaptobenzimidazole Analogs.

Abstract

amino acids is a Vell known phenomenon in animals and has been interpreted as the detoxication of otherwise poisonous substances. The formation of indoleacetylaspartic acid is the first instance of a similar reaction in plants which has come to the attention of the authors. The significance of the reaction in the physiology of the pea is not yet understood. However, the marked difference between plant species with respect to the biosynthesis and utilization of indoleacetylaspartic acid suggests an approach to the problem of selective herbicidal action which may prove useful. The authors wish to acknowledge the technical assistance of A. W. H. Van Ysselstein. LITERATURE CITED 1. ANDREAE, W. A. Communicated at the Congr. Intern. Bot., 8th, Paris. Sect. 11/12: 151. 1954. 2. BoIssoNNAS, R. A. A new method of peptide synthesis. Helv. Chim. Acta 34: 874-879. 1951. 3. JERCHEL, D. and STAAB-MiLLER, R. Analytical characteristics and growth activity of homologs and peptides of indole-3-acetic acid. Zeits. Natturforsch. 9b: 411-415. 1954. 4. TANG, V. W. and BONNER, J. The enzymatic inactivation of indoleacetic acid. II. The physiology of the enzyme. Amer. Jour. Bot. 35: 570-578. 1948. 5. SIEGEL, S. M. and GALSTON, A. WV. Experimental coupling of indoleacetic acid to pea root protein in vivo and in vitro. Proc. Nat. Acad. Sci.. U. S.

Effect of Chemical Structure on the Growth Inhibition of Plants with Some Acid Analogs of 2-Mercaptobenzimidazole.

“…Three chlorine atoms in positions 4, 5 and 6 almost completely removed the growth inhibition of the benzimidazole compound. 4. Nitro-, phenyl-, methyl-, and methoxyl-groups greatly decreased the inhibitory activity and the substitution of two methyl groups in either the 5 and 6 or the 4 and 6 positions almost completely destroyed the ability of these compounds to inhibit the growth of the test plants.…”

“…By using peas as the test plant, Galston et al (1) found that benzimidazole was a metabolic antagonist of adenine and caused an inhibition of cell elongation. Recently Rebstock et al (4) demonstrated that several acid analogs of 2-mercaptobenzimidazole inhibited the growth of Cranberry bean plants and root formation of cucumber seeds.…”

Synthesis of 2-Mercaptobenzimidazole and Some of its Derivatives

“…Besides the (C.H.N.S) analysis Table (3). The FT-IR spectrum of compound [9], indicated the appearance stretching band of (S-S) group at (559) cm -1 with disappearance the bond of (SH) at (2569), these bands and other are show in Table (5),While New compounds [10][11][12][13][14][15][16] were prepared by oxidation thioether to sulfone with used hydrogen peroxide. As is shown below.…”

“…Although a great deal of the scientific literature concerning 2-mercaptobenzimidazole is in the area of medicinal chemistry, 2-mercaptobenzimidazole is also used in non-biological application, it serve as plant growth regulators [12] and used as corrosion inhibitor for mild steel in sulfuric acid solution [13] , stainless steel in aqueous solutionsof NaCl [14] , mild steel and zinc in phosphoric acid [15,16] . Also, it is widely used as an accelerator in rubber processing [17] , and anti oxidant for rubber and plastics [18] .…”

The Effect of Certain Benzazole Compounds on Plant Growth and Development

“…Morphological studies on established plants.-Morphogenic changes in established plants treated with certain aromatic azoles have been partially described by several investigators (Crane, 1952;Dimond and Davis, 1953;Davis, 1954;Rebstock et al, 1955;McCorquodale and Duncan, 1957). Because benzimidazole, benzothiazole and benzotriazole were found to induce characteristic responses in root and shoots of seedlings, it was thought de.…”