2022
DOI: 10.1111/cns.14004
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Inhibition of the expression of rgs‐3 alleviates propofol‐induced decline in learning and memory in Caenorhabditis elegans

Abstract: Background Exposure to anesthesia leads to extensive neurodegeneration and long‐term cognitive deficits in the developing brain. Caenorhabditis elegans also shows persistent behavioral changes during development after exposure to anesthetics. Clinical and rodent studies have confirmed that altered expression of the regulators of G protein signaling (RGS) in the nervous system is a factor contributing to neurodegenerative and psychological diseases. Evidence from preclinical studies has suggested that RGS contr… Show more

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Cited by 2 publications
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