The global challenges that face sustainable sanitation services in developing countries are the lack of fecal sludge management; this is due to the rapid urbanization and population growth as it generates enormous quantities of fecal sludge. The extensive use of unimproved sanitation technologies is one of the main reasons for environmental and public health concerns. In dispersed rural areas, isolated slums or in urban areas where a sewerage system is costly, decentralized wastewater system can be used. Therefore centralized management of decentralized wastewater systems along with proper institutional framework treatment of fecal sludge can be used to enhance the economies of developing counties from resource recovery. The discovery of new ways to inactivate pathogens contained in human waste is key in improving access to sanitation worldwide and reducing the impact of conventional waste management processes on the environment. The entire FS management system should include on-site sanitary treatment methods, collection, and transportation of FS, treatment facilities as well as resource recovery or disposal of the treated end products. This review paper addresses the hygienization of fecal sludge and improved treatment technologies for safe reuse or disposal of the end products and the significant economic revenues attained from the treatments of fecal sludge.