2012
DOI: 10.1016/j.intimp.2012.01.011
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Inhibitory effect of the antidepressant imipramine on NF-κB-dependent CXCL1 expression in TNFα-exposed astrocytes

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Cited by 30 publications
(17 citation statements)
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“…The transcription of the CXCL1 gene is regulated by nuclear factor kappa B (NF-κB)-binding elements within the promoter region (Wood et al ., 1995), and thus the expression of CXCL1 could be NF-kB-dependent as previously suggested (Lee et al ., 2012; Burke et al ., 2014). Interestingly, a recent study suggested that the viral protease 3C pro of CVB3 cleaves inhibitor of kappa B (IκBα), and it was sufficient to cause apoptosis of infected cells (Zaragoza et al ., 2006).…”
Section: Discussionsupporting
confidence: 61%
“…The transcription of the CXCL1 gene is regulated by nuclear factor kappa B (NF-κB)-binding elements within the promoter region (Wood et al ., 1995), and thus the expression of CXCL1 could be NF-kB-dependent as previously suggested (Lee et al ., 2012; Burke et al ., 2014). Interestingly, a recent study suggested that the viral protease 3C pro of CVB3 cleaves inhibitor of kappa B (IκBα), and it was sufficient to cause apoptosis of infected cells (Zaragoza et al ., 2006).…”
Section: Discussionsupporting
confidence: 61%
“…KC (CXCL1) is a chemokine involved in recruiting neutrophils, a type of white blood cell, signaling to microglia (Johnson et al, 2011;De Filippo et al, 2013). Finally, KC signals to the receptor CXCR2, which is expressed on microglia and has been reported to mediate microglial recruitment (Lee et al, 2012). In total, our data show that 40 Hz light flicker stim-ulates the expression of diverse cytokines with both immunomodulatory and neuroprotective properties.…”
Section: Hz Flicker-induced Cytokines Have Neuroprotective Functionsmentioning
confidence: 62%
“…; Lee et al . ). These pathways crosstalk with each other, suggesting a possibility that TdIF1 may regulate ossification through controlling these various signal pathways.…”
Section: Discussionmentioning
confidence: 97%