Inhibitory Effects of Ginger and Beopje Ginger on DSS-induced Colitis in Mice

김신정,; 김소희,; 임양이,; 김용규,; 박건영,

doi:10.3746/jkfn.2014.43.4.477

Cited by 8 publications

(4 citation statements)

References 18 publications

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“…iNOS is known to cause symptoms such as mucosal damage, ulcers, and internal bleeding by overproduction of NO, which is subjected to reaction with superoxide anion ( 20 ). COX-2 was found to worsen inflammatory conditions, and its expression is promoted at inflammation sites of the colonic mucosa ( 11 ).…”

Section: Resultsmentioning

confidence: 99%

“…The plate was analyzed by an ELISA reader to measure light absorbance at 450 nm within 30 min after the final reaction. The optical density value was calculated on the basis of the standard curve obtained from standard samples ( 20 ).…”

Section: Methodsmentioning

confidence: 99%

“…After 40 amplification cycles, a finalization phase was carried out at 72°C for 7 min. The amplified PCR products were run on 1.0% agarose gels, stained with ethidium bromide, and visualized under UV light ( 19 , 20 ).…”

Section: Methodsmentioning

confidence: 99%

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Anti-Colitic Effect of Purple Carrot on Dextran Sulfate Sodium (DSS)-Induced Colitis in C57BL/6J Mice

Kim¹,

Ju²,

Song³

et al. 2018

pnf

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The anti-colitic effect of purple carrot (PC) on 2% dextran sulfate sodium (DSS)-induced colitis in C57BL6/J mice was compared with those of yellow carrot (YC), beet (BT), and red cabbage (RC). Component analysis showed that PC contained cyanidin-3-xyloglucoside, cyanidin-3-xylosyl(sinapoly-glucosyl)galactoside, cyanidin-3-xylosyl(feruloylglucosyl) galactoside, and cyanidin-3-O-(6-O-glycosyl-2-O-xylosylgalactoside). PC diet (5% in AIN 93G diet) strongly reduced DSS-induced colon shortening and inflammatory cell infiltration in mice, followed by RC, BT, and YC diets. Treatment with PC reduced serum levels of pro-inflammatory cytokines such as tumor necrosis factor-α and interleukin-6 as well as reduced mRNA expression in colon tissue of colitis mice in comparison with other treatments. In addition, PC treatment inhibited colonic mRNA expression of inflammatory factors such as inducible nitric oxide synthase and cyclooxygenase-2 in mice. These results suggest that PC can attenuate the inflammatory reaction in mice with DSS-induced colitis, probably due to the anthocyanins in PC.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Anti-Colitic Effect of Purple Carrot on Dextran Sulfate Sodium (DSS)-Induced Colitis in C57BL/6J Mice

Kim¹,

Ju²,

Song³

et al. 2018

pnf

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“…. 생강에 대한 국내 연구는 마우스의 대장염 억제 효과 (Kim et al, 2014), 항산화 효과 (Guon & Chung, 2016;Jung & Park, 2013;Lee et al, 2020), 전립선비대 억제효과 ( Kim et al, 2020), 식품 첨가 관련 연구 (Hwang et al, 2015;Han & Kim, 2011;Lee, 2014) (Kim et al ., 2013a). A, 5 mg/mL; B, 1 mg/mL; C, 0.5 mg/mL; D, 0.25 mg/mL; E, control; -* , No inhibition.…”

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Antibacterial Effect and Deodorization Effect of Extracts from Different Parts of Zingiber officinale

Lee¹,

Kang²,

Ryu³

2020

Asian J Beauty Cosmetol

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Purpose: Using extracts from different parts of Zingiber officinale, we aimed to evaluate its antibacterial effect on skin flora and its deodorization effect on ammonia to determine its potential as an antimicrobial ingredient and functional herbal cosmetic ingredient. Methods: The antibacterial effect on skin flora was examined using the paper disc method and the deodorization effect on ammonia was examined by the gas detection method. Results: After evaluating the antibacterial effects of extracts from different parts (leaves, stems, and roots) of Zingiber officinale, antibacterial activity was observed against Staphylococcus aureus (S. aureus) at a concentration of 5 mg/mL. The leaf, stem, and root extracts had 3 mm, 3 mm, and 2mm clear zones, respectively. For the antibacterial effect against Staphylococcus epidermidis (S. epidermidis), there were 8 mm, 5 mm, and 4mm clear zones for the leaf, stem, and root extracts, respectively. For Propionibacterium acnes (P. acnes), a bacterium that causes acne, there were 4 mm, 3 mm, and 1mm clear zones for the leaf, stem, and root extracts, respectively. The results for Pityrosporum ovale (P. ovale) showed 6 mm, 5 mm, and 4 mm clear zones for the leaf, stem, and root extracts, respectively. For Malassezia furfur (M. furfu), there were 4 mm, 3 mm, and 2 mm clear zones for the leaf, stem, and root extract, respectively. For Candida albicans (C. albicans), there were 4 mm, 3 mm, and 2mm clear zones for the leaf, stem, and root extracts, respectively. Finally, after evaluating the antibacterial effect against Trichophyton mentagrophytes (T. mentagrophytes) at a concentration of 5 mg/mL, we found 6 mm, 4 mm, and 3 mm clear zones for the leaf, stem, and root extracts, respectively. After evaluating the deodorization effects of Zingiber officinale extracts on ammonia, at 120 min, the deodorization effect was 98%, 95%, and 91% for the leaf, stem, and root extracts, respectively. Conclusion: Among the three extracts of Zingiber officinale, the leaf extract had the highest antibacterial effect against the seven types of skin flora as well as the highest deodorization effect, thus confirming its potential as an antibacterial ingredient and functional herbal cosmetic ingredient.

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Processed Gingers: Current and Prospective Use in Food, Cosmetic, and Pharmaceutical Industry

Choi

2019

FNA

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Ginger (Zingiber officinale) has been widely used in traditional medicine, and as raw material for cosmetics, beverages, and health functional foods. However, some adverse effects of ginger have been reported. In addition, the hot and pungent taste of ginger leads to reduced consumption. To overcome these problems, methods for the production of fermented, steamed (or steamed-dried), aged, roasted and beopje ginger have been developed. This review provides an overview and summary of new ginger processing procedures, including methods to reduce the pungent flavor of ginger, extend shelf-life, increase the health-functional compound content, and improve safety. These attempts might improve the consumption of ginger as well as prospective applications of processed ginger for food, cosmetics, and the pharmaceutical industry, also as discussed in various patents.

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Inhibitory Effects of Ginger and Beopje Ginger on DSS-induced Colitis in Mice

Cited by 8 publications

References 18 publications

Anti-Colitic Effect of Purple Carrot on Dextran Sulfate Sodium (DSS)-Induced Colitis in C57BL/6J Mice

Anti-Colitic Effect of Purple Carrot on Dextran Sulfate Sodium (DSS)-Induced Colitis in C57BL/6J Mice

Antibacterial Effect and Deodorization Effect of Extracts from Different Parts of Zingiber officinale

Processed Gingers: Current and Prospective Use in Food, Cosmetic, and Pharmaceutical Industry

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