Initial assessment of the economic burden of major parasitic helminth infections to the ruminant livestock industry in Europe

Charlier, Johannes; Rinaldi, Laura; Musella, Vincenzo; Ploeger, H.W.; Chartier, Christophe; Vineer, Hannah Rose; Hinney, Barbara; Samson‐Himmelstjerna, Georg von; Băcescu, B.; Mickiewicz, Marcin; Mateus, Teresa Letra; Valladares, María Martínez; Quealy, S.; Azaizeh, Hassan; Sekovska, Blagica; Akkari, Hafidh; Petkevičius, Saulius; Hektoen, L.; Höglund, Johan; Morgan, Eric R.; Bartley, David J.; Claerebout, Edwin

doi:10.1016/j.prevetmed.2020.105103

Cited by 260 publications

(181 citation statements)

References 51 publications

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“…Trichostrongyloidea in small ruminants can severely impair animal health and productivity [3]. Common signs of trichostrongylid infections are poor weight gain, weight loss, reduced wool and milk production, diarrhoea, weakness, and ill thrift [8,25,29].…”

Section: Introductionmentioning

confidence: 99%

“…Severe cases can result in sudden death, especially after infections with the blood feeding Haemonchus contortus [2]. Recently, the annual costs of helminth infection in ruminants in Europe was estimated at €1.8 billion (€29 million in Austria) [3]. The control of gastrointestinal nematode (GIN) infections can be roughly categorised into pharmaceutical and non-pharmaceutical approaches (e.g.…”

Section: Introductionmentioning

confidence: 99%

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Multispecific resistance of sheep trichostrongylids in Austria

et al. 2021

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Anthelmintic overuse and failure to implement methods preventing the development and spread of anthelmintic resistance (AR) have led to an alarming increase of resistant ovine trichostrongylids worldwide. The aim of the present study was to determine whether the routine anthelmintic treatment strategy was effective, to obtain insights into the frequency of AR in trichostrongylids of sheep in Austria, and to determine the presence of different trichostrongylid genera. On 30 sheep farms, the faecal egg count reduction test (FECRT) was performed with the Mini-FLOTAC technique in two consecutive studies. In study 1, only fenbendazole and moxidectin were tested, while different compounds and products were used in study 2. Overall, 33 treatment groups were formed: 11 groups were treated with benzimidazoles (fenbendazole and albendazole), 2 groups with avermectins (ivermectin, doramectin), 18 groups with moxidectin, and two groups with monepantel. Reduced efficacy was detected in 64%, 100%, 28% and 50% of these groups, respectively. The most frequently detected genus in larval cultures was Haemonchus, which had been barely detected in Austria previously, followed by Trichostrongylus. Multispecific resistance of trichostrongylids in Austria seems to be on the rise and H. contortus was detected unexpectedly frequently in comparison to previous studies. There is an urgent need to develop efficient communication strategies aimed at improving the engagement of farmers and veterinarians in sustainable parasite control.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Multispecific resistance of sheep trichostrongylids in Austria

et al. 2021

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“…In this study, fascioliasis caused losses of USD 750 million a year, with the largest impact on the dairy and meat cattle industries. 25 The estimated cost of nematode resistance to medications accounted for an additional USD 45 million, but no estimate was provided for resistance in Fasciola. Triclabendazole resistance is a significant problem in some European, Latin American and African countries that may increase the economic burden of fascioliasis.…”

Section: Introductionmentioning

confidence: 99%

<p>Human Fascioliasis: Current Epidemiological Status and Strategies for Diagnosis, Treatment, and Control</p>

Caravedo¹,

Cabada²

2020

RRTM

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Purpose of the Review: This review aims to critically assess current knowledge about the epidemiology, diagnosis, and management of Fasciola infection in humans. Recent Findings: Fascioliasis is an emerging neglected zoonotic infection affecting the health and wellbeing of human populations. The burden of infection is unclear, and studies have shown the geographic expansion of fascioliasis in human and livestock likely related to climate change. The infection can be asymptomatic or present in acute or chronic forms. Regardless of the presentation, fascioliasis can be associated with long-term complications such as anemia and malnutrition. Early in the infection, antibody testing is the only tool available for diagnosis confirmation. In the chronic forms serology and stool microscopy are helpful. Other tests such as antigen detection and PCR-based methods including isothermal tests have shown promising results. Triclabendazole is the only drug available to treat Fasciola infection. However, reports of resistant infections in livestock and human threaten the clinical care and control of the infection in endemic areas. Summary: Fascioliasis is an emerging infection around the world with an uncertain burden. Lack of standardization of diagnostic testing and treatment alternatives hinder treatment and control of the infection.

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“…Helminth infections, mainly by gastrointestinal nematodes (GIN), are one of the main concerns for animal health, welfare and productivity in grazing ruminant livestock worldwide (1,2). In ruminant farm practice, the control of GIN is usually carried out using repeated and sometimes blind anthelmintic treatments, without prior diagnosis of infection.…”

Section: Introductionmentioning

confidence: 99%

A Qualitative Market Analysis Applied to Mini-FLOTAC and Fill-FLOTAC for Diagnosis of Helminth Infections in Ruminants

Maurelli¹,

Martins²,

Morgan³

et al. 2020

Front. Vet. Sci.

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Mini-FLOTAC in combination with the Fill-FLOTAC may be considered a good candidate for a standardized FEC and FECRT in the laboratory, as well as directly in the field, the aim of this study was to conduct SWOT (Strength-Weaknesses-Opportunities-Threats) and PESTEL (Political, Economic, Social, Technological, Environmental, and Legal) analyses of these tools in 20 European countries involved in the COMBAR WG1, in order to identify the opportunities, barriers, and challenges that might affect the Mini-FLOTAC and Fill-FLOTAC commercialization in Europe.

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Initial assessment of the economic burden of major parasitic helminth infections to the ruminant livestock industry in Europe

Cited by 260 publications

References 51 publications

Multispecific resistance of sheep trichostrongylids in Austria

Multispecific resistance of sheep trichostrongylids in Austria

<p>Human Fascioliasis: Current Epidemiological Status and Strategies for Diagnosis, Treatment, and Control</p>

A Qualitative Market Analysis Applied to Mini-FLOTAC and Fill-FLOTAC for Diagnosis of Helminth Infections in Ruminants

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