Initial characterization of a prototype multi-crystal cylindrical SPECT system

Chang, Wei; Huang, Gang; Tian, Zhiyu; Liu, Y.; Kari, B.; Madsen, Mark T.

doi:10.1109/23.159764

Cited by 12 publications

(1 citation statement)

References 7 publications

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“…Single photon emission computed tomography (SPECT) gamma-ray † imaging is widely used in diagnostic nuclear medicine, with appreciable effort having been expended to enhance sensitivity and resolution while simultaneously minimizing patient dose and image acquisition time (Harper et al 1962, 1965, Kuhl and Edwards 1964, Muehllehner 1971, Todd et al 1974, Budinger and Gullberg 1974, Keyes et al 1977, Stokely et al 1980, Kanno et al 1981, Moore et al 1984, Kirsch et al 1981, Williams 1979, Logan and Holmes 1984, Yonekura et al 1989, Chang et al 1992, Kimura et al 1990, Singh 1983, Singh and Doria 1983, Atac et al 1989, Floyd et al 1984, Defrise et al 1989. The efforts are necessitated by the presence of gammas that scatter, or collide, during their transit from source nuclei to the detector as contrasted with gammas that stream, or experience straight-line uncollided transport (Bell and Glasstone 1970).…”

Section: Introductionmentioning

confidence: 99%

SPECT electronic collimation resolution enhancement using chi-square minimization

et al. 1998

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An electronic collimation technique is developed which utilizes the chi-square goodness-of-fit measure to filter scattered gammas incident upon a medical imaging detector. In this data mining technique, Compton kinematic expressions are used as the chi-square fitting templates for measured energy-deposition data involving multiple-interaction scatter sequences. Fit optimization is conducted using the Davidon variable metric minimization algorithm to simultaneously determine the best-fit gamma scatter angles and their associated uncertainties, with the uncertainty associated with the first scatter angle corresponding to the angular resolution precision for the source. The methodology requires no knowledge of materials and geometry. This pattern recognition application enhances the ability to select those gammas that will provide the best resolution for input to reconstruction software. Illustrative computational results are presented for a conceptual truncated-ellipsoid polystyrene position-sensitive fibre head-detector Monte Carlo model using a triple Compton scatter gamma sequence assessment for a 99mTc point source. A filtration rate of 94.3% is obtained, resulting in an estimated sensitivity approximately three orders of magnitude greater than a high-resolution mechanically collimated device. The technique improves the nominal single-scatter angular resolution by up to approximately 24 per cent as compared with the conventional analytic electronic collimation measure.

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