Ankylosing spondylitis (AS) is a chronic inflammatory disease with primary axial skeleton involvement. The main pathological changes include ossification of ligaments, disc annuli, and facet joints, which ultimately leads to spinal rigidity and changes to the spine's biomechanical stability.Also, AS is accompanied by varying degrees of osteopenia or osteoporosis, which further reduces the spine's stability, and even a minimal force can cause spinal fracture (1,2).