Injury to the eye by the sap of Euphorbia royleana.

Sood, Gitanjli; Sofat, B K; Chandel, R D

doi:10.1136/bjo.55.12.856

Cited by 14 publications

(5 citation statements)

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“…Euphorbia latex is cathartic, anthelmintic and used for a variety of conditions such as skin and eye diseases and snakebite (Chopra et al 1958, Basak et al 2009. The latex of Euphorbia royleana produces an intense conjunctival, corneal and iritic inflammatory reaction (Sood et al 1971). Significant antiarthritic activity has been observed in subacute and chronic models of formaldehydeinduced arthritis, adjuvant-induced developing and established arthritis (Bani et al 1998).…”

Section: Introductionmentioning

confidence: 99%

Euphorbia royleana, a botanical pesticide affects ultimobranchial gland of the catfish Heteropneustes fossilis

Prasad¹,

Kumar²,

Srivastav³

et al. 2011

Egypt. J. Bio.

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Heteropneustes fossilis were subjected to high and low doses of the latex of Euphorbia royleana for short-term and long-term exposures, respectively. The blood was analyzed for plasma calcium levels, and the ultimobranchial glands fixed and examined. Serum calcium levels declined after 48 h following short-term exposure, and this decrease continued until the end of the experiment. The ultimobranchial cells exhibited a decrease in the cytoplasmic staining response after 96 h following treatment, and the nuclear volumes slightly decreased. Chronically exposed fish also exhibited a decline in serum calcium levels, but much later, on day 7, again progressively declining until the close of the experiment. Up to day 14 following treatment there was no change in histological structure of the ultimobranchial glands, but then there was a decrease in nuclear volume and the cytoplasm displayed a weak staining response. There was some vacuolization and degeneration.

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Section: Introductionmentioning

confidence: 99%

Euphorbia royleana, a botanical pesticide affects ultimobranchial gland of the catfish Heteropneustes fossilis

Prasad¹,

Kumar²,

Srivastav³

et al. 2011

Egypt. J. Bio.

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“…tirucalli. [ 451112] Only one case of ocular toxicity with E. trigona was reported earlier by Scott et al [5] and they reported only corneal epithelial defect without edema and anterior chamber reaction. But in our Case 1, there was gross corneal edema with moderate anterior uveitis and secondary elevated IOP.…”

Section: Discussionmentioning

confidence: 99%

Keratouveitis caused by Euphorbia plant sap

Basak

Bakshi

Basu

et al. 2009

Indian J Ophthalmol

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The milky sap or latex of Euphorbia plant is highly toxic and an irritant to the skin and eye. This report illustrates the spectrum of ocular inflammation caused by accidental inoculation of latex of Euphorbia plant. Three patients presented with accidental ocular exposure to the milky sap of Euphorbia species of recent onset. The initial symptoms in all cases were severe burning sensation with blurring of vision. Visual acuity reduced from 20/60 to counting fingers. Clinical findings varied from kerato-conjunctivitis, mild to severe corneal edema, epithelial defects, anterior uveitis and secondary elevated intraocular pressure. All symptoms and signs had resolved by 10-14 days with active supportive medication. People who handle Euphorbia plants should wear eye protection. It is always advisable to ask the patient to bring a sample of the plant for identification.

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“…Epiphora, lid swelling, photophobia, chemosis, and anterior-chamber inflammation were also common. [2][3][4][5][6][7][8][9][10][11] Symptoms generally worsened several hours to days after exposure. Final visual acuity was 6/6 in many cases.…”

Section: Discussionmentioning

confidence: 99%