Innovations and advances in cognitive behavioral therapy: Insights from experimental psychopathology

Ouimet, Allison J.; Ferguson, Ryan

doi:10.1177/2043808719874966

Cited by 2 publications

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although there are many ways in which experimental psychopathology research can inform our interventions (e.g. Ouimet & Ferguson, 2019; Van Den Hout et al, 2017; Waters et al, 2017), one appealingly direct route is the application of the procedures or paradigms developed and tested within our experimental work as interventions themselves within clinical settings. One such example is provided by ‘cognitive bias modification’ (CBM) procedures (Koster et al, 2009); these were initially devised to probe the causal role of cognitive biases in experimental settings (e.g.…”

mentioning

confidence: 99%

Making the leap: From experimental psychopathology to clinical trials

Blackwell

Woud

2022

Journal of Experimental Psychopathology

View full text Add to dashboard Cite

One important aim of experimental psychopathology research is to inform development of new interventions derived from basic science. However, testing whether a newly developed intervention is in fact effective requires moving from experimental studies to clinical trials, and this transition can pose many problems. These problems stem not only from the inherent complexity of even the simplest clinical trial but also from differences between experimental psychopathology and clinical trial research that may not always be obvious to researchers immersed in only one of these specialist areas. In this paper, we explore some of these complexities and discuss when a clinical trial may, or may not, be the best next step in the translational process. We then consider some of the ins and outs of clinical trials methodology, from design and planning through to reporting, with the aim of providing a guide for experimental psychopathology researchers thinking of making the leap from their experimental studies of mechanisms to clinical trials of novel interventions. We hope that this can help increase the chance of successful clinical translation and novel treatment development from basic science.

show abstract

mentioning

confidence: 99%