Innovative research of plasma physics for life sciences

Abstract

Abstract. In medicine, cold atmospheric plasma (CAP) for the medical treatment is a new field in plasma application, called plasma medicine. CAP contains mix of excited atoms and molecules, UV photons, charged particles as well as reactive oxygen species (ROS) and reactive nitrogen species (RNS). Typical species in air-CAPs are O 3 , OH, N x O x , and HNO x . The current developments in this field have fuelled the hope that CAP could be an interesting new therapeutic approach in the treatment of cancer. CAP apparently demonstrated effect on cancer cell apoptosis which did not induce cell necrosis or disruption. Moreover, CAP seemed to be selective for cancer cells since it was more effective in tumor cells than in normal nonneoplastic cells. In bioscience, dentistry and veterinary medicine : Since CAP, is delivered at room temperature, which results in less damaging effects on living tissue, while still has the efficiency in disinfection and sterilization. Recent studies proved that it is able to inactivate gram-negative and gram-positive bacteria, fungi, virus, spore, various parasites, and foreign organisms or pathogens without harming tissue. Moreover, cold plasma has been used effectively in medical field such as dental use, inducing apoptosis of malignant cells, stopping bleeding, promoting wound healing and tissue regeneration. Sericin hydrolysates, originating from silkworm is found support cell proliferation, expand cell adhesion and increase cell yield. The covalent linkage between a bioactive protein molecule and polystyrene dish surface via a carbon intermediate layer can slow down the release rate of protein compound into the phosphate buffer saline (PBS) solution. We found that a-C films and a-C:N 2 films show good attachment of human bone marrow-derived mesenchymal stem cells (hBM-MSCs). All of carbon modified-Polystyrene(PS) dishes revealed the less release rate of sericin molecules into PBS solution than PS control.

Cold plasma: a potential new method to manage postharvest diseases caused by fungal plant pathogens

“…A number of reviews have demonstrated the efficacy of CP in medicine and dentistry (Boonyawan, ; Laroussi et al ., ; Weltmann & von Woedtke, ; Xu et al ., ). According to Heinlin et al .…”

Effects on phenotypic and genotypic modifications of low-pressure radiofrequency capacitively coupled plasma treatment of Thai purple glutinous rice seeds

“…A body of O-dominated cold plasma is formed between the upper and bottom electrodes after the electrodes are triggered and controlled oxygen gas is fed into the reactor chamber. As mentioned above, the plasma is composed of charged particles, such as ions and electrons, neutrals and ROS, as well as ultraviolet light (which also assists in the ROS production), as diagonalized in various experiments (such as Steinbruchel et al, 1986, as a very early one), including those by the members of the current authros (Boonyawan, 2017, Kosumsupamala et al, 2022. As the bottom electrode is biased with -500 V, the ions have a higher concentration near the bottom electrode (above which the seeds are placed) than near the upper electrode (while electrons have the opposite concentration distribution), as illustrated in Fig.…”