Flexible surface acoustic wave (SAW) sensors in the frequency range of 162~325 MHz were developed based on single crystalline LiNbO 3 thin film with dual resonance modes, namely the Rayleigh mode and thickness shear mode (TSM). This SAW sensor could handle a wide strain range up to ±3500 µε owing to its excellent flexibility, which is nearly six times the detecting range of bulk piezoelectric substrate based SAW strain sensors. The sensor exhibited a high sensitivity of 193 Hz/µε with a maximum hysteresis less than 1.5%, much better than those commercially available metallic strai gauges. The temperature coefficients of frequency, for Rayleigh and TSM modes, were-85 and-59 ppm/℃, respectively. No visible deterioration was observed after cyclic bending for hundreds of times, showing its desirable stability and reliability. By utilizing the dual modes, the strain sensor with a self-temperature calibrated capability can be achieved. The results demonstrate that the sensor is an excellent candidate for strain sensing.