Inorganic Scintillators in Positron Emission Tomography

Eijk, C.W.E. van

doi:10.1007/1-4020-5093-3_11

Cited by 5 publications

(5 citation statements)

References 42 publications

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“…The lithium atoms occupy six independent positions and are surrounded by four or five oxygen atoms. The symmetry of both Y 3+ and Gd 3+ ion sites is C1 (distorted cube) [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25]. Both LGBO and LYBO crystallizes in the monoclinic system with the space group P2 1 /c with the refined parameters measured on the fibers single crystals grown by micro-pulling down technique as can seen in Table 1.…”

Section: +mentioning

confidence: 99%

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Ce-doped Li6Ln(BO3)3 (Ln=Y, Gd) Single crystals fibers grown by micro-pulling down method and luminescence properties

et al. 2013

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Section: +mentioning

confidence: 99%

“…Van Eijk et al [9,10] has suggested that LGBO crystals will have a high light yield (about 15,000 photons/MeV) and short decay times (s % 27 ns). As 6 Li, 10 B, Gd,155 Gd isotopes can react with the neutrons and then produce charged particles c rays with…”

Section: +mentioning

confidence: 99%

Ce-doped Li6Ln(BO3)3 (Ln=Y, Gd) Single crystals fibers grown by micro-pulling down method and luminescence properties

et al. 2013

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“…When testing LYSO, it was found that the observed lifetime (∼46 ns) was longer than 40 ns reported in the literature. 25 This led us to investigate LYSO response times and energy resolutions for various scintillator geometries. Annihilation energy spectra were generated using two similar Hamamatsu R1924A single channel PMTs each coupled to one of the two different sizes of LYSO: a block measuring 30 × 15 × 15 mm 3 and a thin rectangle measuring 30 × 22 × 2 mm 3 coupled to the PMT at the 2 × 22 mm 2 face.…”

Section: A Testing Of Scintillators and Mounting Arrangementsmentioning

confidence: 99%

Detector for positronium temperature measurements by two-photon angular correlation

Cecchini

Jones

Fuentes-Garcia

et al. 2018

Review of Scientific Instruments

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We report on the design and characterization of a modular γ-ray detector assembly developed for accurate and efficient detection of coincident 511 keV back-to-back γ-rays following electron-positron annihilation. Each modular detector consists of 16 narrow lutetium yttrium oxyorthosilicate scintillators coupled to a multi-anode Hamamatsu H12700B photomultiplier tube. We discuss the operation and optimization of 511 keV γ-ray detection resulting from testing various scintillators and detector arrangements concluding with an estimate of the coincident 511 keV detection efficiency for the intended experiment and a preliminary test representing one-quarter of the completed array.

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“…A 1 mm diameter 18 F point source was positioned in the center of scanner FOV emitting mono-energetic back-to-back 511 keV photons. In the simulation, the energy window was set to 250-700 keV, and the energy resolution was based on the reported energy resolutions for each of the scintillator materials.…”

Section: Validation Of Monte Carlo Simulation Tool With the Vista Sca...mentioning

confidence: 99%

“…The spatial resolution across the FOV of the VISTA scanner was simulated by moving a 0.5 mm diameter 18 F point source, with 5 mm increments along radial direction, from central point to 25 mm away from the central slice. For each of the source positions, source image was reconstructed using two dimensional filtered backprojection (FBP) method.…”

Section: Validation Of Monte Carlo Simulation Tool With the Vista Sca...mentioning

confidence: 99%

Characterization of three layer depth of interaction PET detectors for small animal imaging

Behnamian

Shafiee

2018

Biomed. Phys. Eng. Express

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High sensitivity and spatial resolution are two main parameters of each small animal imaging system. Multi-layers phoswich detectors have been developed to measure the depth of interaction and to improve system spatial resolution. In the past, efforts have been made to develop these kinds of detectors with different crystal materials and lengths. In this work, three layers phoswich detectors based on GE Healthcare eXplore VISTA PET scanner geometry composing LYSO, GSO and BGO scintillators with different crystal orders and lengths were investigated to find the optimum case with the highest sensitivity and uniform spatial resolution. All simulations were performed using the Monte Carlo simulation tool, the Geant4 Application for Tomographic Emission (GATE). In order to validate GATE simulation package, the GE eXplore VISTA small animal PET system was modeled and output results were compared with the experimental data. The length of each of the three layers varied, while the total length (LYSO + GSO + BGO) was fixed at 15 mm. The order of these crystal layers was also changed, so that totally we have considered 55×6=330 different configurations. Using three layer phoswich detector, a 25%-68% improvement in the sensitivity at central slice was found compared to the dual layer VISTA PET scanner, dependent on different detector configurations. In this study, among all posible configurations, detector length permutations with higher efficiency values (12×6=72 cases) were choosen to evaluate spatial resolution. The radial and tangential spatial resolutions were markedly improved for all studied different detector configurations compared to the VISTA PET scanner. Among all the possible selected detector configurations, LYSO (4 mm) + GSO (4 mm) + BGO (7 mm) and BGO (5 mm) + LYSO (5 mm) + GSO (5 mm) cases gave the best DOI radial and tangential resolutions for an energy threshold of 250 keV, respectively. In the LYSO (4 mm) + GSO (4 mm) + BGO (7 mm) scanner configuration, the radial resolution was kept below 1.154 mm, over 25 mm field of view (FOV). The tangential resolution variations were minimized to less than 1.029 mm, over 25 mm FOV, using the BGO (5 mm) + LYSO (5 mm) + GSO (5 mm) detector type. As a result, our new designed three layers phoswich detectors with excellent DOI resolution will lead to small animal PET scanners with higher sensitivity and uniform spatial resolution across the FOV.

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Inorganic Scintillators in Positron Emission Tomography

Cited by 5 publications

References 42 publications

Ce-doped Li6Ln(BO3)3 (Ln=Y, Gd) Single crystals fibers grown by micro-pulling down method and luminescence properties

Ce-doped Li6Ln(BO3)3 (Ln=Y, Gd) Single crystals fibers grown by micro-pulling down method and luminescence properties

Detector for positronium temperature measurements by two-photon angular correlation

Characterization of three layer depth of interaction PET detectors for small animal imaging

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