Insecticidal Activity of the Methanol Extracts of Some Tunicate Species against Aedes aegypti and Anopheles maculatus

Hussein, Zeti Azura Mohd; Jantan, Ibrahim; Awaludin, Alma; Ahmad, Nazni Wasi

doi:10.1076/phbi.39.3.213.5922

Cited by 5 publications

(1 citation statement)

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“…Extracts or essential oils from plants may be alternative sources of mosquito larval control agents, since they constitute a rich source of bioactive compounds that are biodegradable into nontoxic products. It has been reported that many plant products present activity against mosquito larvae Aedes aegypti (Hussein et al 2001;Rodrigues et al 2005;Cheng et al 2008). In several studies, it was shown that para-benzoquinones contribute to this activity (Rodrigues et al 2005;Cheng et al 2008;Ribeiro et al 2009).…”

Section: Introductionmentioning

confidence: 96%

Larvicidal activity of para-Benzoquinones

et al. 2010

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Plant products may be alternative sources of mosquito larval control agents, since they constitute a rich source of bioactive compounds that are biodegradable into nontoxic products. It has been reported that quinones and derivatives present toxic activity against mosquito larvae Aedes aegypti. Therefore, these facts led us to investigate the larvicidal potential of six structurally related para-benzoquinones against A. aegypti L. (Culicidae) larvae, the vector of dengue fever. All the para-benzoquinones were found to have larvicidal effect. The unsubstituted para-benzoquinone was the compound that exhibited the lowest potency, while 2-isopropyl-para-benzoquinone was the most bioactive. In general, the presence of alkyl groups results in more potent compounds. In addition, the number, position, and size of these groups modulate the potency of the compounds. The experimental results showed that by appropriate structural modification of para-benzoquinones, it may be possible to develop novel insecticidal compounds with potential use to control A. aegypti population.

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