Inserting Menthoxytriazine into Poly(ethylene terephthalate) for Inhibiting Microbial Adhesion

Abstract

Antimicrobial modification of poly­(ethylene terephthalate) (PET) is effective in preventing the adhesion and growth of microorganisms on its surface. However, few methods are available to modify PET directly at its backbone to impart the antimicrobial effect. Herein, menthoxytriazine-modified PET (PMETM) based on the stereochemical antimicrobial strategy was reported. This novel PET was prepared by inserting menthoxytriazine into the PET backbone. The antibacterial adhesion test and the antifungal landing test were employed to confirm the antiadhesion ability of PMETM. PMETM could effectively inhibit the adhesion of bacteria, with inhibition ratios of 99.9 and 99.7% against Escherichia coli (Gram-negative) and Bacillus subtilis (Gram-positive), respectively. In addition, PMETM exhibited excellent resistance to Aspergillus niger (fungal) contamination for more than 30 days. Cytotoxicity assays indicated that PMETM was a noncytotoxic material. These results suggested that the insertion of menthoxytriazine in the PET backbone was a promising strategy to confer antimicrobial properties to PET.

Dual Coordination between Stereochemistry and Cations Endows Polyethylene Terephthalate Fabrics with Diversiform Antimicrobial Abilities for Attack and Defense

“…niger and M. racemosus were chosen as typical fungal strains to assess the ability of the fabric to resist fungal adhesion according to the previously reported method. , First, 2 μL of the fungal suspension was added to the center of the plate. Next, the circular fabric (diameter = 15 mm) was placed approximately 15 mm from the center.…”

Antimicrobial Modification of PET by Insertion of Menthoxy-Triazine

“…The antifungal properties of PEMT were studied by "antifungal landing test" according to previously reported method. 39 PEMT was pressed into a regular circular sheet with a diameter of 13 mm and a thickness of 0.75 mm. A preprepared suspension of 2 μL of A. niger suspension at a concentration of 10 6 CFU mL −1 was added to the center of the wort medium.…”

“…The antifungal properties of PEMT were studied by “antifungal landing test” according to previously reported method . PEMT was pressed into a regular circular sheet with a diameter of 13 mm and a thickness of 0.75 mm.…”

Targeted Anti-Biofilm Therapy: Dissecting Targets in the Biofilm Life Cycle

“…Inspired by hydration ability of zwitterionic brushes, Hong et al grafted 2-methacryloyloxyethyl phosphate choline (MPC) onto medical devices, which can effectively inhibit formation of biofilm [ 92 ]. Wang et al proposed a stereochemical antibacterial strategy to achieve an anti-adhesion effect through the selective differentiation of L/D molecules by bacteria [ 93 ]. Antognazza et al patterned silk film substrates that could effectively reduce adhesion of bacteria [ 94 ].…”