Insight into the phase inversion of a turmeric oil nanoemulsion in antifungal process

Lin, Yongxing; Liu, Jia; Gao, Yanjin; Li, Rui; Qin, Zini; Guan, Yongguang

doi:10.1111/ijfs.14722

Cited by 7 publications

(3 citation statements)

References 26 publications

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“…While this method is not yet widely used in ophthalmic nanoemulsion characterization, it will definitely be adopted in the near future, providing novel insight into structure of colloidal nanosize drug delivery systems. 88 − 90 …”

Section: Ocular Nanoemulsions Research Methodsmentioning

confidence: 99%

“…Although classical electron microscopy techniques (TEM or SEM) require staining and/or drying of nanoemulsions that may affect the size and shape of the nanodroplets, a cryoEM provides the unique oportunity to directly image the obtained colloidal systems without major structural changes. While this method is not yet widely used in ophthalmic nanoemulsion characterization, it will definitely be adopted in the near future, providing novel insight into structure of colloidal nanosize drug delivery systems. − …”

Section: Ocular Nanoemulsions Research Methodsmentioning

confidence: 99%

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Ophthalmic Nanoemulsions: From Composition to Technological Processes and Quality Control

et al. 2021

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Nanoemulsions are considered as the most promising solution to improve the delivery of ophthalmic drugs. The design of ophthalmic nanoemulsions requires an extensive understanding of pharmaceutical as well as technological aspects related to the selection of excipients and formulation processes. This Review aims at providing the readers with a comprehensive summary of possible compositions of nanoemulsions, methods for their formulation (both laboratory and industrial), and differences between technological approaches, along with an extensive outline of the research methods enabling the confirmation of in vitro properties, pharmaceutical performance, and biological activity of the obtained product. The composition of the formulation has a major influence on the properties of the final product obtained with low-energy emulsification methods. Increasing interest in high-energy emulsification methods is a consequence of their scalability important from the industrial perspective. Considering the high-energy emulsification methods, both the composition and conditions of the process (e.g., device power level, pressure, temperature, homogenization time, or number of cycles) are important for the properties and stability of nanoemulsions. It is advisible to determine the effect of each parameter on the quality of the product to establish the optimal process parameters’ range which, in turn, results in a more reproducible and efficient production.

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Section: Ocular Nanoemulsions Research Methodsmentioning

confidence: 99%

Section: Ocular Nanoemulsions Research Methodsmentioning

confidence: 99%

Ophthalmic Nanoemulsions: From Composition to Technological Processes and Quality Control

et al. 2021

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“…Similarly, a turmeric-based oil-in-water nanoemulsion was prepared and applied to determine its antifungal activity against Podosphaera xanthii. The results of the study revealed that the turmeric oil nanoemulsion of turmeric inhibited fungus growth and showed a remarkable antifungal effect [96].…”

Section: Nanoemulsionsmentioning

confidence: 99%

Antimicrobial Potential of Curcumin: Therapeutic Potential and Challenges to Clinical Applications

et al. 2022

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Curcumin is a bioactive compound that is extracted from Curcuma longa and that is known for its antimicrobial properties. Curcuminoids are the main constituents of curcumin that exhibit antioxidant properties. It has a broad spectrum of antibacterial actions against a wide range of bacteria, even those resistant to antibiotics. Curcumin has been shown to be effective against the microorganisms that are responsible for surgical infections and implant-related bone infections, primarily Staphylococcus aureus and Escherichia coli. The efficacy of curcumin against Helicobacter pylori and Mycobacterium tuberculosis, alone or in combination with other classic antibiotics, is one of its most promising antibacterial effects. Curcumin is known to have antifungal action against numerous fungi that are responsible for a variety of infections, including dermatophytosis. Candidemia and candidiasis caused by Candida species have also been reported to be treated using curcumin. Life-threatening diseases and infections caused by viruses can be counteracted by curcumin, recognizing its antiviral potential. In combination therapy with other phytochemicals, curcumin shows synergistic effects, and this approach appears to be suitable for the eradication of antibiotic-resistant microbes and promising for achieving co-loaded antimicrobial pro-regenerative coatings for orthopedic implant biomaterials. Poor water solubility, low bioavailability, and rapid degradation are the main disadvantages of curcumin. The use of nanotechnologies for the delivery of curcumin could increase the prospects for its clinical application, mainly in orthopedics and other surgical scenarios. Curcumin-loaded nanoparticles revealed antimicrobial properties against S. aureus in periprosthetic joint infections.

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Food emulsions with biopolymers

Nguyen,

Kha

2024

Advances in Biopolymers for Food Science and Technology

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Insight into the phase inversion of a turmeric oil nanoemulsion in antifungal process

Abstract: A phase inversion of essential oil nanoemulsion droplets from oil‐in‐water to water‐in‐oil types during moisture evaporation after spraying onto plant leaves is one of the primary mechanisms to expose the essential oil in ambient environment and to play its antimicrobial activity.

Cited by 7 publications

References 26 publications

Ophthalmic Nanoemulsions: From Composition to Technological Processes and Quality Control

Ophthalmic Nanoemulsions: From Composition to Technological Processes and Quality Control

Antimicrobial Potential of Curcumin: Therapeutic Potential and Challenges to Clinical Applications

Food emulsions with biopolymers

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