Insights Into Management of Atrial Fibrillation in Asia Pacific Gained From Baseline Data from REgistry on Cardiac rhythm disORDers (RecordAF-Asia Pacific [AP]) Registry

Non-vitamin K antagonist oral anticoagulants (NOACs) for stroke prevention in Asian patients with atrial fibrillation: Time for a reappraisal

“…Specific data on associated comorbidities from surveys and cohort studies of AF from various Asian countries, compared to non-Asians are summarized in Table 1 [3,[9][10][11][12][13][14][15]. The average age and proportion of females in Asians and non-Asians were broadly similar.…”

Time Trends of Aspirin and Warfarin Use on Stroke and Bleeding Events in Chinese Patients With New-Onset Atrial Fibrillation

“…In the Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation (RECORD-AF), in which 52% of patients were taking warfarin and 42%, aspirin, the Asian subgroup (RECORD-AF-Asia Pacifi c study) involved 2,721 patients (36% Chinese) and reported that 36% were on warfarin and 51% were on aspirin from 2007 to 2008. 18 Th e diff erence in warfarin use in the RECORD-AF-Asia Pacifi c study and in this study could perhaps be related to prescribing habits (a province in China vs other Asia-Pacifi c countries with advanced health-care systems) or the data source, especially since RECORD-AF is an industry-funded commercial study and the present study is based on an administrative dataset. Th e rate of warfarin use in RECORD-AF-Asia Pacifi c probably represents the level of warfarin use in other Asian countries apart from China (ie, only 951 Chinese among the 2,629 Asian patients).…”

“…Th e rate of warfarin use in RECORD-AF-Asia Pacifi c probably represents the level of warfarin use in other Asian countries apart from China (ie, only 951 Chinese among the 2,629 Asian patients). 18 Similarly, the Reduction of Atherothrombosis for Continued Health (REACH) Registry recruited 16% Asian and 0.1% Chinese patients. 19 Among 4,582 patients with AF (90% of patients with CHADS 2 score Ն 1), the rate of warfarin use was 52% (including 16% taking warfarin plus an antiplatelet medication) and aspirin was used in 50%, with a 7.7% stroke rate over a 4-year follow-up.…”

“…[17][18][19][20][21] In these studies, about one-half of the patients with AF were given warfarin and the rates of warfarin use were much lower in the Asian subgroup with AF. 17,18 Aspirin was still the common antithrombotic drug used.…”

“…[17][18][19][20][21] In these studies, about one-half of the patients with AF were given warfarin and the rates of warfarin use were much lower in the Asian subgroup with AF. 17,18 Aspirin was still the common antithrombotic drug used. In the Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation (RECORD-AF), in which 52% of patients were taking warfarin and 42%, aspirin, the Asian subgroup (RECORD-AF-Asia Pacifi c study) involved 2,721 patients (36% Chinese) and reported that 36% were on warfarin and 51% were on aspirin from 2007 to 2008.…”