Instant Nutritional Assessment: Absolute Weight Loss and Surgical Mortality

Seltzer, Murray H.; Slocum, Bernadette A.; Cataldi-Betcher, Emma L.; Fileti, Cecilia; Gerson, Noel Bertram

doi:10.1177/0148607182006003218

Cited by 98 publications

(37 citation statements)

References 21 publications

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“…Weight loss of ≥5% in 1 month or ≥10% in 6 months is a generally accepted cutoff for clinically relevant weight loss. Weight loss of ≥5% in 1 month or ≥10% in 6 months is associated with increased morbidity such as impaired wound healing, reduced immune function and decreased tolerance to surgery, radiotherapy and chemotherapy and with increased mortality [2,25,28]. Besides that, weight loss of ≥5% in 1 month or ≥10% in 6 months has a negative impact on disease-related quality of life and functional status [27].…”

Section: Discussionmentioning

confidence: 99%

“…We used involuntary weight loss of ≥5% in 1 month or ≥10% in 6 months as the cutoff point for CWL because it appeared to be of great prognostic value in the occurrence of major post-operative complications and is associated with higher mortality and complication rate [2,25,28]. CWL is an indicator of recently developed malnutrition risk [1,4].…”

Section: Discussionmentioning

confidence: 99%

“…The first part assessed CWL, defined as weight loss of ≥5% in 1 month or ≥10% in 6 months [1,2,4,8,25,28]. Assessment of CWL was based upon the formula [normal weight (kg)−actual weight (kg)]/normal weight (kg)× 100%].…”

Section: Methodsmentioning

confidence: 99%

“…It is associated with increased morbidity and mortality. CWL may result in an increased complication rate, such as impaired wound healing, reduced immune function and decreased tolerance to surgery, radiotherapy and chemotherapy [2,25,28]. CWL also reduces disease-related quality of life and functional status [27].…”

Section: Introductionmentioning

confidence: 99%

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Critical weight loss in head and neck cancer—prevalence and risk factors at diagnosis: an explorative study

Jager‐Wittenaar

Dijkstra

Vissink

et al. 2007

Support Care Cancer

165

132

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Goals of work Critical weight loss (≥5% in 1 month or ≥10% in 6 months) is a common phenomenon in head and neck cancer patients. It is unknown which complaints are most strongly related to critical weight loss in head and neck cancer patients at the time of diagnosis. The aim of this explorative study was to assess the prevalence of critical weight loss and to analyze risk factors for critical weight loss in head and neck cancer patients before treatment. Materials and methods Critical weight loss and factors reducing dietary intake were assessed in 447 patients referred to an ear, nose and throat clinic at the time of diagnosis. Main results In total, data of 407 patients were analyzed. Critical weight loss was present in 19% of the patients. Patients with cancer in the hypopharynx, oropharynx/oral cavity and supraglottic larynx had the highest risk for critical weight loss. Loss of appetite, dysphagia/passage difficulties and loss of taste/aversion were significantly (p<0.05) associated with critical weight loss. Conclusions Already before treatment, critical weight loss is a considerable problem in head and neck cancer patients. Critical weight loss is frequently observed in patients with cancer in the hypopharynx, oropharynx/oral cavity and supraglottic larynx.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Critical weight loss in head and neck cancer—prevalence and risk factors at diagnosis: an explorative study

Jager‐Wittenaar

Dijkstra

Vissink

et al. 2007

Support Care Cancer

165

132

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“…As in the current study, negative outcomes at 6 months have been reported for the physical and head and neck specific concerns, largely reflecting the ongoing trouble with swallowing, social eating, dry mouth, sticky saliva, and mouth opening in the irradiated population 78,79 . In addition, weight loss of 10% or more in 6 months, as found in the current study, has been associated with increased morbidity such as impaired wound healing, reduced immune function, and increased mortality, and has also been shown to impact on quality of life and functional outcomes [80][81][82][83] .…”

Section: Six Months Post-treatmentmentioning

confidence: 95%

A Prospective Investigation of Swallowing, Nutrition, and Patient-rated Functional Impact Following Altered Fractionation Radiotherapy with Concomitant Boost for Oropharyngeal Cancer

et al. 2011

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Altered fractionation radiotherapy for head and neck cancer has been associated with improved locoregional control, overall survival, and heightened toxicity compared with conventional treatment. Swallowing, nutrition and patient-perceived function for altered fractionation radiotherapy with concomitant boost (AFRT-CB) for T1-T3 oropharyngeal SCC has not been previously reported. Fourteen consecutive patients treated with AFRT-CB for oropharyngeal SCC were recruited from November 2006 to August 2009 in a tertiary hospital in Brisbane, Australia. Swallowing, nutrition and patient-perceived functional impact assessments were conducted pre-treatment, at 4-6 weeks post-treatment and at 6 months posttreatment. Deterioration from pre-treatment to 4-6 weeks post-treatment in swallowing, nutrition and functional impact was evident, likely due to the heightened toxicity associated with AFRT-CB. There was significant improvement at 6 months post-treatment in functional swallowing, nutritional status, patient-perceived swallowing and overall function, consistent with recovery from acute toxicity. However, weight and patient-perception of their physical function and side effects remained significantly worse than pre-treatment scores. The ongoing deficits related to weight and patient-perceived outcomes at 6 months revealed this treatment has a long-term impact on function possibly related to the chronic effects of AFRT-CB.

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Improved Pressure Sore Healing With Hydrocolloid Dressings

Gorse¹,

Messner²

1987

Arch Dermatol

103

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We prospectively followed inpatients receiving treatment for pressure sores to identify the better of two local treatment regimens. Twenty-seven patients with 76 pressure sores received treatment with hydrocolloid dressings (HCDs) and 25 patients with 52 pressure sores received treatment with Dakin's solution (chloramine-T)-soaked wet-to-dry dressings. Thirty-eight (73%) patients initially had severe nutritional depletion. The mean serum albumin value of the pressure sore treatment groups was lower than that of an age-matched group without pressure sores. In the HCD group, 66 (86.8%) pressure sores improved compared with 36 (69.2%) pressure sores in the wet-to-dry dressings group. The HCD regimen was more efficacious even in a subgroup of patients who received inadequate nutritional support during treatment. Adequate nutritional intake during the study was associated with better healing in both local treatment groups.

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Instant Nutritional Assessment: Absolute Weight Loss and Surgical Mortality

Cited by 98 publications

References 21 publications

Critical weight loss in head and neck cancer—prevalence and risk factors at diagnosis: an explorative study

Critical weight loss in head and neck cancer—prevalence and risk factors at diagnosis: an explorative study

A Prospective Investigation of Swallowing, Nutrition, and Patient-rated Functional Impact Following Altered Fractionation Radiotherapy with Concomitant Boost for Oropharyngeal Cancer

Improved Pressure Sore Healing With Hydrocolloid Dressings

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