Insuficiencia renal aguda inducida por rabdomiolisis

Nieto­-Ríos, John Fredy; Vega-Miranda, Juliana; Higuita, Lina María Serna

doi:10.17533/udea.iatreia.v29n2a05

Cited by 2 publications

(2 citation statements)

References 24 publications

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“…Associations of Anti-infective accounted for 51.5% (34) of the identified pDDI, mainly explained by the association between vancomycin and amikacin (31). The non-antimicrobial drugs that individually presented a higher prevalence of pDDI with antimicrobials were simvastatin (22.7%, 15, C -Cardiovascular System) and warfarin (10.6%, 7, S -Blood and Hematopoietic Organs).…”

Section: Resultsmentioning

confidence: 99%

Clinically relevant drug interactions involving antimicrobials in a general hospital: a cross-sectional study

Pavanello¹,

Farhat²,

Carvalho³

et al. 2021

Rev Bras Farm Hosp Serv Saude

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Objective: To assess the prevalence of pDDI involving antimicrobials and other standardized drugs in a large general hospital in the interior of São Paulo. Methods: quantitative study, with cross-sectional design and data collection by documentary analysis of hospital prescriptions from April to June 2017. Results: 66 clinically relevant pDDI were found, which corresponded to approximately 7.3% of antimicrobial prescriptions, being 93.9% (62) contraindicated / severe and 6.1% (4) moderate. There was no difference in the prevalence of clinically relevant pDDIs between critical and non-critical inpatient, in addition to all contraindicated interactions (10) having occurred in the clinical and surgical units. The most prevalent pDDI were, with respective degrees of documentation, between vancomycin and amikacin (47% - reasonable), clarithromycin and simvastatin (13.6% - good), and ciprofloxacin and simvastatin (7.6% - good). Conclusion: For the proper prevention of potential drug-related problems, mechanisms to guarantee the quality of prescriptions by trained clinical pharmacists are of fundamental importance, in addition to alert systems and drug interaction information for the health team, then ensuring quality pharmacotherapy and patient safety.

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Section: Resultsmentioning

confidence: 99%

Clinically relevant drug interactions involving antimicrobials in a general hospital: a cross-sectional study

Pavanello¹,

Farhat²,

Carvalho³

et al. 2021

Rev Bras Farm Hosp Serv Saude

View full text Add to dashboard Cite

show abstract

“…However, the average of the samples, more influenced by color perception on each collection day (figure 1), indicates that none of the urine was in a hydrated state (24). Electrolyte imbalances, including dehydration, are significant contributors to muscle damage and, subsequently, the development of rhabdomyolysis (30,31). Highly concentrated and excessively alkaline urine can lead to false positive results concerning altered renal function.…”

Section: Discussionmentioning

confidence: 99%