Insulin improves well-being for selected elderly type 2 diabetic subjects

The Effects of Interventions on Health-Related Quality of Life Among Persons With Diabetes

“…2,[52][53][54][55] Characteristics of the study participants are shown in 32,38,46 and 11 pre-post-design studies. 3,7,8,19,21,22,29,30,36,37,40 These studies examined a wide range of interventions, including diabetes education and behavioral modification (15 studies), 3,7,8,21,22,32,39,40,42,43,45,[47][48][49][50] pharmacotherapy (11 studies), 19,20,26,28,31,[33][34][35][36]38,44 and surgery (7 studies). 27,29,30,37,41,46,…”

“…7,46 Second, in some control groups receiving different interventions, improvements were more marked than in intervention groups. 19,28,34,44 Our review has several limitations. First, heterogeneity among study designs, types and focus of interventions, length of follow-up, and the characteristics of participants made between-study comparisons and stratification difficult.…”

“…In this review, we found that 2 studies of the effects of insulin therapy showed small improvements in HRQL that may be independent of glycemic control. 3,34 One study 44 comparing insulin therapy to oral agents showed significant improvement in mental health, social functioning, and vitality with insulin, but not in the group receiving oral agents.…”

Heterogeneity of change in state affect following insulin therapy initiation in type 2 diabetic patients

“…However, the short follow-up period (a month since the introduction of insulin therapy) does not allow to reliably predict either further changes in the patients' affect trajectories, as well as proportions of patients constituting various affect-based classes after insulin therapy initiation. As the previously cited studies suggest, positive psychological effects of insulin therapy may be short-lived (Reza et al, 2002), therefore further research covering longer time periods needs to be undertaken. When the above-described four subgroups were compared in terms of sociodemographic variables, only modest intergroup differences were found.…”

“…increased BMI after the insulin therapy initiation (Brown et al, 2000). It is also emphasized that insulin therapy may yield only short-term improvements in psychological outcomes (Reza, Taylor, Ward, & Hendra, 2002), which might be associated with reduction of distressing bodily sensations (hyperglycemia; Davis, Clifford, & Davis, 2001). In the light of the discrepant research findings cited above, indicating patients' ambiguous evaluation of insulin therapy, it seems justified to further investigate this issue.…”