Insulin Pen Injection Devices for Management of Patients with Type 2 Diabetes: Considerations Based on an Endocrinologist’s Practical Experience in the United States

Thurman, Jerome E.

doi:10.4158/ep.13.6.672

Cited by 33 publications

(16 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This largest comparative study carried out so far revealed an excellent dosing accuracy for all tested insulin pens, with none of the single values (1,260 in total) at all dose levels being outside the defined range of the ISO recommendation. Previously reported dosing outside the ISO limits 5,6,10 could not be verified in this study.…”

mentioning

confidence: 99%

“…1 They offer several advantages over the traditional vial-and-syringe method, such as reduced pain during injection, discretion of use, easy portability, and fewer claims for hypoglycemic events. [2][3][4] Because of these advantages the use of insulin pens is widespread, particularly in Europe.…”

mentioning

confidence: 99%

“…[2][3][4] Because of these advantages the use of insulin pens is widespread, particularly in Europe. 1 As patients rely heavily upon device accuracy to administer the correct amount of insulin, the accuracy of insulin pens is an important issue. Insulin pens are available in two types: reusable and disposable insulin pens.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Study on the Dosing Accuracy of Commonly Used Disposable Insulin Pens

Krzywon

Burg

Fuhr

et al. 2012

Diabetes Technology & Therapeutics

View full text Add to dashboard Cite

Background: Improved patient comfort and optimal glycemic control have led to the widespread use of insulin pens, particularly in Europe. Most of the former studies on the dose accuracy of insulin pens included only a small number of doses and pens. In extension to our previous large-scale study testing the dosing accuracy following a randomized dosing sequence with each pen, the present study was more directed toward the dose accuracy for one specific dose dispensed repeatedly with the same pen. This is the first study providing detailed comparative data on the accuracy of repeated dose delivery with prefilled disposable insulin pens at low, middle, and high doses, dispensed over the entire pen volume. Results: All tested insulin pens met the requirements for accuracy with none of the single values being outside the defined range of the ISO recommendations (1 -1 units, 30 -1.5 units, and 60 -3 units, respectively). Conclusion:The present study demonstrated a consistent and accurate dose delivery at all dosage levels for all tested insulin pens, with no clinically relevant differences among the products.

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Study on the Dosing Accuracy of Commonly Used Disposable Insulin Pens

Krzywon

Burg

Fuhr

et al. 2012

Diabetes Technology & Therapeutics

View full text Add to dashboard Cite

show abstract

“…Numerous reports of insulin pen technology state that insulin pens can make insulin administration easier for individuals with visual impairment and dexterity impairment. 1,[4][5][6][7] Yet very few clinical studies of insulin pens have included persons with either of these disabilities, and those that do commonly exclude individuals with severe impairment. Moreover, no published study was found that included persons who have both dexterity and visual impairments, yet this combination is not uncommon among persons with diabetes.…”

Section: In This Issue Of Journal Of Diabetes Science and Technologymentioning

confidence: 99%

Analysis: Linking Laboratory Data to Human Factors and Inclusion of Persons with Disabilities in Diabetes Technology Research

Williams

2011

J Diabetes Sci Technol

View full text Add to dashboard Cite

In this issue of Journal of Diabetes Science and Technology, Friedrichs and colleagues present a study of the injection force of four reusable insulin pens and another study of the dosing accuracy of three different insulin pens. For the study of injection force, the authors claim that lower injection force has numerous advantages for patients, including making use of pens easier for people with decreased hand strength. For the study of dosing accuracy, the authors state that dose accuracy is critical for glycemic control.Both study designs have significant strengths, including measurements of the variable of interest using two different methodologies and thorough documentation of methods and materials. However, the careful, precise measurements of injection force and dosing accuracy are not matched by equivalent precision supporting the significance of the studies. The authors do not provide any information about what measured injection force is easy or difficult for individuals with and without manual problems or what level of dosing inaccuracy is clinically significant. Therefore, the implications for practice remain unclear. Data about these and other relevant human factors are needed to provide meaningful context for laboratory measurements of diabetes technologies. Furthermore, researchers conducting studies of diabetes technology that include human subjects should intentionally recruit persons with disabilities so diabetes care professionals can know whether and how technical information about diabetes technology applies to the full range of patients, including those with disabilities.

show abstract

“…Nurses, diabetes educators, and pharmacists have a particularly important role in educating patients on how to use insulin pens because incorrect use can affect pen performance and thus the accuracy of the administered dose. 16 This review describes the practical aspects of insulin pen devices, including considerations when selecting among different insulin pens.…”

Section: Introductionmentioning

confidence: 99%

Practical Aspects of Insulin Pen Devices

Pearson

2010

J Diabetes Sci Technol

View full text Add to dashboard Cite

Insulin pen devices have several advantages over the traditional vial-and-syringe method of insulin delivery, including improved patient satisfaction and adherence, greater ease of use, superior accuracy for delivering small doses of insulin, greater social acceptability, and less reported injection pain. In recent years, pens have become increasingly user-friendly, and some models are highly intuitive to use, requiring little or no instruction. Despite this progress, uptake of these devices in the United States has not matched that in many other areas of the world. There is a need for improved awareness of the current characteristics of insulin pen devices among United States health care professionals. Knowledge of the design improvements that have been incorporated into pens, both to address patient needs and as a result of the improved technology behind the device mechanics, is essential to promoting the use of insulin pen devices. This review highlights some of the practical aspects of pen use and discusses the factors to be considered when selecting among different insulin pens.

show abstract

Insulin Pen Injection Devices for Management of Patients with Type 2 Diabetes: Considerations Based on an Endocrinologist’s Practical Experience in the United States

Cited by 33 publications

References 20 publications

Study on the Dosing Accuracy of Commonly Used Disposable Insulin Pens

Study on the Dosing Accuracy of Commonly Used Disposable Insulin Pens

Analysis: Linking Laboratory Data to Human Factors and Inclusion of Persons with Disabilities in Diabetes Technology Research

Practical Aspects of Insulin Pen Devices

Contact Info

Product

Resources

About