Insulin-pen treatment, quality of life and metabolic control: retrospective intra-group evaluations

Hörnquist, Jan Olof; Wikby, Anders; Andersson, Per‐Olof; Dufva, Ann-Mari

doi:10.1016/0168-8227(90)90065-2

Cited by 57 publications

(21 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…31 The simplicity of insulin pen devices facilitates not only good glycaemic control, but also contributes to improved quality of life. 32 The development of finer, shorter needles has also helped to alleviate the pain of injections. In a recent study, needles with a smaller outer diameter caused significantly less pain than larger needles.…”

Section: Addressing Risk For Cardiovascular Diseasementioning

confidence: 99%

When oral agents fail: practical barriers to starting insulin

2002

View full text Add to dashboard Cite

Insulin therapy has proven benefits in Type 2 diabetes patients when combination therapy has failed. However, there is some reluctance by both patients and healthcare professionals to initiate insulin therapy. This reluctance has been termed 'psychological insulin resistance'. Barriers to the initiation of insulin therapy include patients' fear of disease progression and needle anxiety; mutual concerns about hypoglycaemia and weight gain; and health professionals' use of insulin as a threat to encourage compliance with earlier therapies. It is essential that these obstacles are identified and investigated as a means of overcoming these impediments to recommended levels of glycaemic control, an initiative being pursued by the DAWN study. Where concerns are tangible, such as fear of hypoglycaemia, therapeutic solutions can be pursued. Overcoming psychological barriers relies more on innovative management techniques. Improving insulin delivery to meet these needs, coupled with enhanced healthcare services, can address psychological insulin resistance and contribute to the maintenance of good metabolic control.

show abstract

Section: Addressing Risk For Cardiovascular Diseasementioning

confidence: 99%

When oral agents fail: practical barriers to starting insulin

2002

View full text Add to dashboard Cite

show abstract

“…[12][13][14] Collectively, these features of insulin pens have enabled diabetes patients to lead more flexible and lessrestrictive lives, leading to improved quality of life. [15][16][17] However, continued improvements in injection-system technology seek to improve both the ease of use and patient satisfaction with the injection process. Previous studies have indicated that the diameter and design of the needle play an important role in reducing injection pain and needle anxiety in subcutaneous insulin delivery and in improving patient satisfaction.…”

mentioning

confidence: 99%

Needle with a Novel Attachment Versus Conventional Screw-Thread Needles: A Preference and Usability Test Among Adults with Diabetes and Impaired Manual Dexterity

Hansen

Lilleøre²,

Ter-Borch³

2011

Diabetes Technology & Therapeutics

View full text Add to dashboard Cite

Background: NovoTwist Ò (Novo Nordisk A/S, Bagsvaerd, Denmark) is an insulin pen needle that features a novel attachment and detachment system. The aim of this test was to assess overall preference and handling of NovoTwist compared with conventional screw-thread needles in people with type 1 or type 2 diabetes. Methods: One hundred twenty adults with type 1 or type 2 diabetes and manual dexterity dysfunction who were currently self-injecting with an insulin pen were included in this open-label, randomized, crossover test. Participants were stratified according to the impact that manual dexterity problems had on their ability to inject insulin (1 ¼ no effect at all; 4 ¼ a lot), and those rated as 1 were excluded from subanalyses because of low numbers. Following instruction, participants attached the needle to Next Generation FlexPen Ò (Novo Nordisk A/S), made an injection into a foam cushion, and detached the needle; this process was repeated three times with NovoTwist and the participant's current screw-thread needle (or NovoFine Ò [Novo Nordisk A/S]) in a random order. Responses to questions on user experience with each needle were subsequently recorded on a 6-point rating scale (1 ¼ very difficult; 6 ¼ very easy). Results: Significantly more respondents had a preference for NovoTwist (79%) compared with the conventional screw-thread needles (21%, P < 0.001). Significantly more respondents preferred NovoTwist for both ease of attachment (80%, P < 0.001) and ease of detachment (74%, P < 0.001). Most respondents found NovoTwist the most appropriate needle for performing everyday injections (71%, P < 0.001). Conclusions: Such preference by patients has a positive impact on the treatment of diabetes as NovoTwist may alleviate the burden of performing everyday injections through its ease of use.

show abstract

“…17,18 Insulin pens have been developed to help address these issues, with resulting improvements in portability, dosing accuracy, mealtime flexibility, and convenience of delivery. [4][5][6]19 Increased patient preference, treatment satisfaction, and quality of life have been reported for pen devices compared with the vial and syringe; 3,7,20,21 these benefits may be particularly important due to their demonstrated impact on patient adherence. Other studies have shown that pen devices are associated with improved costs of care, less reported injection pain, and improved patient self-management behaviors, including adherence to treatment, compared with the vial and syringe.…”

Section: Advantages Of Pen Devices Compared With Vial and Syringesmentioning

confidence: 99%

Practical Aspects of Insulin Pen Devices

Pearson

2010

J Diabetes Sci Technol

View full text Add to dashboard Cite

Insulin pen devices have several advantages over the traditional vial-and-syringe method of insulin delivery, including improved patient satisfaction and adherence, greater ease of use, superior accuracy for delivering small doses of insulin, greater social acceptability, and less reported injection pain. In recent years, pens have become increasingly user-friendly, and some models are highly intuitive to use, requiring little or no instruction. Despite this progress, uptake of these devices in the United States has not matched that in many other areas of the world. There is a need for improved awareness of the current characteristics of insulin pen devices among United States health care professionals. Knowledge of the design improvements that have been incorporated into pens, both to address patient needs and as a result of the improved technology behind the device mechanics, is essential to promoting the use of insulin pen devices. This review highlights some of the practical aspects of pen use and discusses the factors to be considered when selecting among different insulin pens.

show abstract

Insulin-pen treatment, quality of life and metabolic control: retrospective intra-group evaluations

Cited by 57 publications

References 19 publications

When oral agents fail: practical barriers to starting insulin

When oral agents fail: practical barriers to starting insulin

Needle with a Novel Attachment Versus Conventional Screw-Thread Needles: A Preference and Usability Test Among Adults with Diabetes and Impaired Manual Dexterity

Practical Aspects of Insulin Pen Devices

Contact Info

Product

Resources

About