Insulin sensitivity following treatment with the ??1-blocker bunazosin retard and the ??1-blocker atenolol in hypertensive non-insulin-dependent diabetes mellitus patients

Endocrine abnormalities in healthy first‐degree relatives of type 2 diabetes patients – potential role of steroid hormones and leptin in the development of insulin resistance

“…Glucose uptake was calculated at steady-state during the final 40 min of the clamp (80 -120 min) on the basis of the amount of glucose infused. It was divided by the steady-state plasma glucose concentration to correct for differences in the acquired glucose levels [20], which obviously were different in the two centres according to the protocols used. Thus, the metabolic clearance rate of glucose (MCR) was obtained, and MCR was expressed per lean body mass, LBM, in order to adjust for different degrees of adiposity.…”

No Direct Link between Albumin Excretion Rate and Insulin Resistance - A Study in Type 1 Diabetes Patients with Mild Nephropathy

“…The M-value was calculated by dividing the glucose infusion rate by body weight (mg/kg/min). Insulin sensitivity index (ISI) is a measure of tissue sensitivity to insulin adjusted for the prevailing insulin level, and was calculated by dividing the M-value by the mean insulin concentration during the same period of the clamp (100 mg/kg/min/ (mU/l) [30,31]. The metabolic clearance rate for insulin (MCR ins ) was calculated at steady state by dividing insulin infusion rate with the mean serum insulin level measured at 60, 90 and 120 min (ml/kg/min) [32].…”

Effect of Cilnidipine on Insulin Sensitivity in Patients with Essential Hypertension

“…Some of the widely used antihypertensive agents have been demonstrated to modify insulin sensitivity and also alter the atherogenic risk profiles. β-Adrenoceptor blockers and thiazides decrease insulin sensitivity and worsen dyslipidemia (9)(10)(11)(12), and angiotensin-converting enzyme (ACE) inRecently, cilnidipine, a long acting Ca-channel antagonist that blocks both L-and N-type Ca 2 -channels, has become available in Japan. The N-type Ca 2 -channel exists specifically in neural cells.…”