The paper studies peculiarities of formation and use of the Yamal–Nenets Autonomous Okrug labour potential. The purpose of the study is to identify the specifics of the situation in the regional labour market, its main determinants and development prospects, and to formulate proposals for employment policy corresponding to the peculiarities of the socio-demographic and economic situation. The paper is based on state labour statistics, municipal statistics, information of the Federal Register of Disabiled Persons, and the Rosstat population surveys data. To solve the research tasks the author uses methods of descriptive statistical analysis, as well as clustering methods in application to data characterizing tensions in the labour market of the municipalities of the region. The results of the analysis indicate the high role of migration in the formation of the labour potential of the region. Among the structural features of employment of the Yamal–Nenets Autonomous Okrug are a significant share of shift labour and a high proportion of migrants in the labour force, significant disparities in the structure of employed by economic activity and occupational group, as well as a small proportion of self-employed and entrepreneurs. The author concludes that the problems of the labour market act as an obstacle to the sustainable development of the region.