“…With an embedded force sensing unit, the system is capable of ensuring the threshold force is never surpassed and in the case of a biological medium, the object being manipulated retains its properties and viability. Multiple force sensing methods have been shown for micromanipulation or microrobotic applications, such as piezoelectric/piezoresistive [ 21 , 22 , 23 , 24 ], atomic force microscope (AFM) [ 25 , 26 ], vision-based [ 11 , 27 ], and capacitive [ 28 , 29 ]. From these methods, a vision-based force sensor modality is selected for use here since it is able to overcome many of the drawbacks other sensors, such as high costs and difficult integration with micromanipulation systems (AFM sensors), complicated circuitry (capacitive sensors), and temperature sensitivity (piezoresistive sensors).…”